CYP2C9

CYP2C9 on Wikipedia (opens in tab)
CYP2C9 on PubChem (opens in tab)
List
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by rifampin. The enzyme is known to metabolize many xenobiotics, including phenytoin, tolbutamide, ibuprofen and S-warfarin. Studies identifying individuals who are poor metabolizers of phenytoin and tolbutamide suggest that this gene is polymorphic. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. [provided by RefSeq, Jul 2008]
JUMP TOSUBSTRATESINDUCERSINHIBITORS
CYP11A1   *
CYP11B1   *
CYP11B2   *
CYP17A1   *
CYP19A1
CYP1A1
CYP1A2
CYP1B1
CYP21A2
CYP24A1   *
CYP27A1   *
CYP2A1   *
CYP2A6
CYP2B1   *
CYP2B2   *
CYP2B6
CYP2C11   *
CYP2C18   *
CYP2C19
CYP2C8
CYP2C9
CYP2D6
CYP2E1
CYP2J2
CYP2S1
CYP3A11   *
CYP3A2   *
CYP3A4
CYP3A5
CYP3A7
CYP4A1   *
CYP4B1
CYP4F11   *
CYP4F22   *
CYP51A1   *

  * Non-Human
Amitriptyline
Arachidonic acid → Epoxyeicosatetraenoic acids
Bisphenol A
Celecoxib
Diclofenac
Docosahexaenoic acid → Epoxydocosapentaenoic acids
Eicosapentaenoic acid → Epoxyeicosatetraenoic acids
Fluoxetine
Fluvastatin
Glibenclamide
Glimepiride
Glipizide
Glyburide
Ibuprofen
Irbesartan
Lornoxicam
Losartan
Meloxicam
Nateglinide
Phenytoin-4-OH
Pitavastatin
Rosiglitazone
Rosuvastatin
S-naproxen,Norpiroxicam
S-warfarin
Suprofen
Tamoxifen
Tolbutamide
Torsemide
Valproic acid
Zakirlukast
Carbamazepine
Coleus forskohlii
Enzalutamide
Hypericum perfoliatum
Nevirapine
Phenobarbital
Rifampin
Secobarbital

All spice oil
Amiodarone   (moderate)
Baicalein
Bergamot oil
Cardamom oil
Carrot seed oil
Chloramphenicol
Cimetidine
Cimicifuga racemosa   (weak)
Cinnamon leaf oil
Cinnamon oil
Citronella oil
Clary sage oil
Cranberry juice
Curcumin
Efavirenz
Elemi oil
Esomeprazole
Felbamate
Fenofibrate
Fluconazole
Fluoxetine
Fluvastatin
Fluvoxamine
Garlic   (waek)
Ginkgo biloba   (weak)
Honokiol
Hydrastic canadensis   (strong)
Indomethacin
Isochlorogenic acid A
Isoniazid
Ketoconazole
Lansoprazole
Lovastatin
Metronidazole
Modafinil
Omeprazole
Oral contraceptives
Oregano oil
Oxcarbazepine
Pantoprazole
Paroxetine
Phenylbutazone
Probenicid
Resveratrol
Sertraline
Silybum marianum   (strong)
Sulfamethoxazole
Sulfaphenazole
Sulforaphane
Teniposide
Ticlopidine
Topiramate
Voriconazole
Zafirlukast

CYPRESS™ IS A REGISTERED TRADEMARK ® OF DATAPUNK BIOINFORMATICS, LLC. COPYRIGHT © 2015, 2016, 2017 ALL RIGHTS RESERVED.    |    DEVELOPER BLOG     |