Lurp

Cross-platforn SNP explorer. By Peter D'Adamo, ND


i6018900

Hard Link
i6018900 is a snp on gene SULT1A1 (sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1)

GeneSULT1A1 Chromosome number 20 Chromosome position 48062699
Alleles A/C/T Minor Allele C Minor Allele Frequency 0.0321
Notation *2 ↓ rs1042028 638G>A R213H Arg135His Clinical significance Orientation (dbSNP) + (positive/forward strand)
SNP Function
Missense variant rs1042028.
Gene Function
Sulfotransferase enzymes (SULTs) enable the addition of sulfate to many hormones, neurotransmitters, phenolic drugs, and toxic environmental compounds. SULT1A1 is an important phase II detoxificiation enzyme. They have protein-protein interactions with DIO1 and 2 enzymes. In contrast to other Phase II enzymes, SULT1A1 can convert a number of procarcinogens (such as heterocyclic amines from cooked meats) into highly reactive intermediates which may act as chemical carcinogens and mutagens. SULT1A1 helps the safe elimination of acetominophen. Sulfotransferases are inhibited by quercetin, red wine, black and green tea, caffeine and carmoisine in red food coloring.
This SNP is reported by one or more services.


23andme V3

NOT REPORTED




23andme V4

REPORTED




23andme V5

NOT REPORTED




Ancestry DNA

NOT REPORTED




Genos Export for Promethease

NOT REPORTED




Opus 23 Curated

CURATED




CLINVAR Curated

NOT CURATED




GWAS Curated

NOT CURATED





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