Lurp

Cross-platforn SNP explorer. By Peter D'Adamo, ND


rs12095080

Hard Link
rs12095080 is a snp on gene DIO1 (deiodinase, iodothyronine, type I)

GeneDIO1 Chromosome number 1 Chromosome position 53911057
Alleles A/G Minor Allele G Minor Allele Frequency 0.0933
Notation D1b *1058A>G Clinical significance Orientation (dbSNP) + (positive/forward strand)
SNP Function
3’ UTR variant.
Gene Function
The DIO1 gene provides instructions for making a protein enzyme called propylthiouracil-sensitive oxidoreductase that activates thyroid hormone by converting the hormone thyroxine (T4), produced in the thyroid, to the active bioactive hormone triiodothyronine (T3). It also degrades both hormones. Some versions of this enzyme contain selenocysteine, a compound based on selenium.
This SNP is reported by one or more services.


23andme V3

REPORTED




23andme V4

NOT REPORTED




23andme V5

NOT REPORTED




Ancestry DNA

NOT REPORTED




Genos Export for Promethease

NOT REPORTED




Opus 23 Curated

CURATED




CLINVAR Curated

NOT CURATED




GWAS Curated

NOT CURATED





MOST RECENT SEARCHES:
rs4880 (SOD2) | rs13063628 (THRB) | rs225014 (DIO2) | rs12885300 (DIO2-AS1) | rs12095080 (DIO1) | rs1991517 (LOC101928462) | rs2235544 (DIO1) | rs651852 (BHMT) | rs1801131 (MTHFR) | rs1799853 (CYP2C9) | rs1801181 (CBS)

MOST FREQUENTLY SEARCHED:
rs9939609 (FTO) | rs1799941 (SHBG) | rs1801133 (MTHFR) | rs2844682 (MUC21) | rs2569191 (CD14) | rs6025 (F5) | rs4680 (COMT) | rs20541 (IL13) | rs1801181 (CBS) | rs2075252 (LRP2) | rs2476601 (PTPN22)








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