Lurp

Cross-platforn SNP explorer. By Peter D'Adamo, ND


rs1801282

Hard Link
rs1801282 is a snp on gene PPARG (peroxisome proliferator-activated receptor gamma)

GenePPARG Chromosome number 3 Chromosome position 12351626
Alleles C/G Minor Allele G Minor Allele Frequency 0.0703
Notation -2-28078C>G Pro12Ala Clinical significance Orientation (dbSNP) + (positive/forward strand)
SNP Function
ADIPOQ -11391G>A rs17300539 and ADIPOQ -11377C>G rs266729
Gene Function
This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described.
GWAS Pathologies
Type 2 diabetes (C) ~ Fasting insulin-related traits (interaction with BMI) (?) ~ Type 2 diabetes (C) ~ Type 2 diabetes (C) ~ Type 2 diabetes (C)
This SNP is reported by one or more services.


23andme V3

REPORTED




23andme V4

REPORTED




23andme V5

REPORTED




Ancestry DNA

REPORTED




Genos Export for Promethease

REPORTED




Opus 23 Curated

CURATED




CLINVAR Curated

CURATED




GWAS Curated

CURATED





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