Lurp

Cross-platforn SNP explorer. By Peter D'Adamo, ND


rs2296972

Hard Link
rs2296972 is a snp on gene HTR2A (5-hydroxytryptamine (serotonin) receptor 2A)

GeneHTR2A Chromosome number 13 Chromosome position 46854336
Alleles C/A (transliterated to +) Minor Allele A Minor Allele Frequency 0.3774
Notation 614-18697T>G Clinical significance Orientation (dbSNP) - (negative/reverse strand)
SNP Function
Intron variant.
Gene Function
This gene encodes one of the receptors for serotonin, a neurotransmitter with many roles. Mutations in this gene are associated with susceptibility to schizophrenia and obsessive-compulsive disorder, and are also associated with response to the antidepressant citalopram in patients with major depressive disorder (MDD). This receptor was first given importance as a target of serotonergic psychedelic drugs such as LSD. Later it came back to prominence because it was also found to be mediating, at least partly, the action of many antipsychotic drugs, especially the atypical ones. Genetic variations between individuals in the HTR2A gene may to some extent account for the difference in outcome of antidepressant treatment.
This SNP is reported by one or more services.


23andme V3

REPORTED




23andme V4

REPORTED




23andme V5

NOT REPORTED




Ancestry DNA

REPORTED




Genos Export for Promethease

NOT REPORTED




Opus 23 Curated

CURATED




CLINVAR Curated

NOT CURATED




GWAS Curated

NOT CURATED





MOST RECENT SEARCHES:
rs1799971 (OPRM1) | rs6003 (F13B) | rs4344931 (AGXT) | rs121912855 (COL7A1) | rs10974944 (JAK2) | rs12272004 (CHR11-LOC116603724) | rs510769 (OPRM1) | rs2296972 (HTR2A-AS1) | rs622337 (HTR2A-AS1) | rs4251417 (SLC6A4) | rs2873804 (DBH)

MOST FREQUENTLY SEARCHED:
rs9939609 (FTO) | rs1801133 (MTHFR) | rs1799941 (SHBG) | rs6025 (F5) | rs4680 (COMT) | rs1801181 (CBS) | rs2569191 (CD14) | rs20541 (IL13) | rs2235544 (DIO1) | rs2075252 (LRP2) | rs2844682 ()








LURP™ IS A REGISTERED TRADEMARK ® OF DATAPUNK BIOINFORMATICS, LLC. COPYRIGHT © 2015, 2016, 2017, 2018 ALL RIGHTS RESERVED.    |    DEVELOPER BLOG     |