Lurp

Cross-platforn SNP explorer. By Peter D'Adamo, ND


rs779710

Hard Link
rs779710 is a snp on gene GRM7 (glutamate receptor, metabotropic 7)

GeneGRM7 Chromosome number 3 Chromosome position 7469688
Alleles T/C (transliterated to +) Minor Allele C Minor Allele Frequency 0.4848
Notation Clinical significance Orientation (dbSNP) - (negative/reverse strand)
Gene Function
L-glutamate is the major excitatory neurotransmitter in the central nervous system, and it activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors that have been divided into three groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5, and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3, while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Multiple transcript variants encoding different isoforms have been found for this gene. 
This SNP is reported by one or more services.


23andme V3

REPORTED




23andme V4

REPORTED




23andme V5

REPORTED




Ancestry DNA

REPORTED




Genos Export for Promethease

NOT REPORTED




Opus 23 Curated

NOT CURATED




CLINVAR Curated

NOT CURATED




GWAS Curated

NOT CURATED





MOST RECENT SEARCHES:
rs11122562 () | rs779710 (GRM7) | rs1047781 (FUT2) | rs601338 (FUT2) | rs492602 (FUT2) | rs150384171 (CD320) | rs6277 (DRD2) | rs4880 (SOD2) | rs13063628 (THRB) | rs225014 (DIO2) | rs12885300 (DIO2-AS1)

MOST FREQUENTLY SEARCHED:
rs9939609 (FTO) | rs1801133 (MTHFR) | rs1799941 (SHBG) | rs2844682 (MUC21) | rs6025 (F5) | rs2075252 (LRP2) | rs4680 (COMT) | rs2569191 (CD14) | rs20541 (IL13) | rs1801181 (CBS) | rs2235544 (DIO1)








LURP™ IS A REGISTERED TRADEMARK ® OF DATAPUNK BIOINFORMATICS, LLC. COPYRIGHT © 2015, 2016, 2017 ALL RIGHTS RESERVED.    |    DEVELOPER BLOG     |