Lurp

Cross-platforn SNP explorer. By Peter D'Adamo, ND


rs9939609

Hard Link
rs9939609 is a snp on gene FTO (fat mass and obesity associated)

GeneFTO Chromosome number 16 Chromosome position 53786615
Alleles A/T Minor Allele A Minor Allele Frequency 0.3401
Notation 46-23525A>T Clinical significance Orientation (dbSNP) + (positive/forward strand)
SNP Function
Intronic.
Gene Function
Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes. in 2009 variants in the FTO gene were further confirmed to associate with obesity in two very large genome wide association studies of body mass index (BMI).   A study of 38,759 Europeans for variants of FTO identified several obesity risk alleles. The presence of  FTO variations was also found to be positively correlated with other symptoms of the metabolic syndrome, including higher fasting insulin, glucose, and triglycerides, and lower HDL cholesterol. 
GWAS Pathologies
Type 2 diabetes (A) ~ Menarche (age at onset) (A) ~ Biomedical quantitative traits (A) ~ Body mass index (A) ~ Type 2 diabetes (A) ~ Body mass index (A)
This SNP is reported by one or more services.


23andme V3

REPORTED




23andme V4

REPORTED




23andme V5

REPORTED




Ancestry DNA

REPORTED




Genos Export for Promethease

NOT REPORTED




Opus 23 Curated

CURATED




CLINVAR Curated

NOT CURATED




GWAS Curated

CURATED





MOST RECENT SEARCHES:
rs13063628 (THRB) | rs225014 (DIO2) | rs12885300 (DIO2-AS1) | rs12095080 (DIO1) | rs1991517 (LOC101928462) | rs2235544 (DIO1) | rs651852 (BHMT) | rs1801131 (MTHFR) | rs1799853 (CYP2C9) | rs1801181 (CBS) | rs1801394 (MTRR)

MOST FREQUENTLY SEARCHED:
rs9939609 (FTO) | rs1799941 (SHBG) | rs1801133 (MTHFR) | rs2569191 (CD14) | rs20541 (IL13) | rs2844682 (MUC21) | rs4680 (COMT) | rs2476601 (PTPN22) | rs6025 (F5) | rs2075252 (LRP2) | rs1801181 (CBS)








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