Linoleic acid metabolism - Homo sapiens (human)

Curator(s): Stephanie Soualt, Generative Medicine Class

Linoleic acid (LA) is a polyunsaturated fatty acid used in the biosynthesis of arachidonic acid (AA) and thus some prostaglandins. It is found in the lipids of cell membranes. It is abundant in many vegetable oils, comprising over half (by weight) of poppy seed, safflower, sunflower, and corn oils.Linoleic acid is an essential fatty acid that must be consumed for proper health. A diet only deficient in linoleate causes mild skin scaling, hair loss, and poor wound healing.    
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Linoleic acid metabolism - Homo sapiens (human) Linoleate node2 1.14.14.1 Linoleate->node2 node7 1.13.11.60 Linoleate->node7 node8 1.13.11.45 Linoleate->node8 node12 5.2.1.5 Linoleate->node12 node16 1.149933 Linoleate->node16 node17 1.14.19.3 Linoleate->node17 node22 1.13.11.58 Linoleate->node22 node29 1.13.11.12 Linoleate->node29 node30 1.13.11.33 Linoleate->node30 Lecithin node1 3.1.1.4 Lecithin->node1 node1->Linoleate node3 9(10)-EpOME node2->node3 node14 12(13)-EpOME node2->node14 node4 9,10 -12,13 -Diepoxy-octadecanoate node3->node4 node10 3.3.2.- node3->node10 node5 9,10 -Dihydroxy -12,13-epoxyoctadecanoate node4->node5 node6 THF-diols node5->node6 node9 8(R)-HPODE node7->node9 node20 11(S)-HPODE node8->node20 node35 5.4.4.6 node9->node35 node11 9,10-DHOME node10->node11 node15 12,13-DHOME node10->node15 node13 9-cis,11 -trans-Octadecadenoate node12->node13 node14->node4 node14->node10 Crepenyate node16->Crepenyate node18 gamma-Linolenate node17->node18 node19 Dihomo -gamma -linolenate node18->node19 Arachidonate node19->Arachidonate Arachidonic acid metabolism Arachidonate->Arachidonic acid metabolism node21 9(S)-HPODE node23 9(S)-HODE node21->node23 node25 9,10 -Epoxy -13-hydroxy -11-octadecenoate node21->node25 node27 12,13 -Epoxy -9-hydroxy -10-octadecenoate node21->node27 node22->node21 node24 9-OxoODE node23->node24 node23->node27 node26 9,10,13-TriHOME node25->node26 node28 9,12,13-TriHOME node27->node28 node31 13(S)-HPODE node29->node31 node30->node31 node31->node27 node32 13(S)-HODE node31->node32 node33 1.1.1.- node32->node33 node34 13-OxoODE node33->node34 node36 (7S,8S)-DiHODE node35->node36 print "
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