Taurine and hypotaurine metabolism - Homo sapiens (human)

Curator(s): Vanessa Doyle

Taurine, or 2-aminoethanesulfonic acid, is an organic acid widely distributed in animal tissues. It is a major constituent of bile and can be found in the large intestine and accounts for approximately 0.1% of total human body weight. Taurine has many fundamental biological roles such as conjugation of bile acids, antioxidation, osmoregulation, membrane stabilization and modulation of calcium signaling. It is essential for cardiovascular function, and development and function of skeletal muscle, the retina and the central nervous system. Taurine is unusual among biological molecules in being a sulfonic acid, while the vast majority of biologically occurring acids contain the more weakly acidic carboxyl group. While taurine is sometimes called an amino acid, and indeed is an acid containing an amino group, it is not an amino acid in the usual biochemical meaning of the term, which refers to compounds containing both an amino and a carboxyl group. | KEGG Map |    

Zoom out 50% Move left to zoom out, right to zoom in Zoom in 50% 100%

Taurine and hypotaurine metabolism - Homo sapiens (human) Taurine Taurocyamine Taurine->Taurocyamine Excretion Taurine->Excretion node12 Taurine->node12 node13 Taurine->node13 node14 Taurine->node14 node1 5-Glutamyl -taurine node11 Taurocyamine->node11 Taurocyamine phosphate Hypotaurine node6 Hypotaurine->node6 Cysteamine node9 Cysteamine->node9 node2 L-Cysteine node2->Cysteamine node4 node2->node4 node10 node2->node10 node3 L-Cysteate node7 node3->node7 node8 node3->node8 node5 3-Sulfino -L-alanine node4->node5 node5->Hypotaurine node5->node3 node6->Taurine node7->Taurine node8->Taurine node9->Hypotaurine node10->node3 node11->Taurocyamine phosphate node12->node1 Taurocholate node13->Taurocholate Aminoacetaldehyde node14->Aminoacetaldehyde Sulfite node14->Sulfite Sulfoacetaldehyde node15 Sulfoacetaldehyde->node15 node15->Sulfite node16 node16->Taurine node16->Sulfoacetaldehyde node17 L-Alanine node16->node17 Pyruvate node16->Pyruvate node18 2 Pyruvate->node18 Pyruvate node19 node19->node17 node19->Pyruvate print "