Lurp

Cross-platforn SNP explorer. By Peter D'Adamo, ND


rs1041983

Hard Link
rs1041983 is a snp on gene NAT2 (N-acetyltransferase 2 (arylamine N-acetyltransferase))

GeneNAT2 Chromosome number Chromosome position
Alleles (transliterated to +) Minor Allele Minor Allele Frequency
Notation Tyr94Tyr Clinical significance Orientation (dbSNP) - (negative/reverse strand)
Gene Function
NAT2 encodes a critical Phase II detoxification enzyme that functions to both activate and deactivate arylamine and hydrazine drugs and carcinogens. Polymorphisms in this gene are responsible for the N-acetylation polymorphism in which human populations segregate into rapid, intermediate, and slow acetylator phenotypes. Polymorphisms in this gene are also associated with higher incidences drug toxicity. Carcinogens resulting from grilled and barbequed foods are processed by NAT2 and compromised NAT2 function affords a higher risk for colorectal cancer in those eating well-cooked meats.
This SNP is reported by one or more services.


23andme V3

REPORTED




23andme V4

REPORTED




23andme V5

REPORTED




Ancestry DNA

REPORTED




Genos Export for Promethease

REPORTED




DSL/ Opus Chip

REPORTED




Opus 23 Curated

CURATED




CLINVAR Curated

NOT CURATED




GWAS Curated

NOT CURATED





MOST RECENT SEARCHES:
rs36010656 () | rs174556 () | rs9282861 (SULT1A1) | rs1799732 () | i5007206 (MAT1A) | rs2994388 () | rs4933327 () | rs2993763 (MAT1A) | rs7097297 () | rs10509413 () | rs1832683 ()

MOST FREQUENTLY SEARCHED:
rs429358 (APOE) | rs9939609 (FTO) | rs1799941 (SHBG) | rs1801133 (MTHFR) | rs1801181 (CBS) | rs4680 (COMT) | rs6025 (F5) | rs20541 (IL13) | rs2569191 (CD14) | rs2235544 (DIO1) | rs2187668 (HLA-DQA1)








LURP ™ IS A REGISTERED TRADEMARK ® OF DATAPUNK BIOINFORMATICS, LLC. COPYRIGHT © 2015, 2016, 2017, 2018, 2019 ALL RIGHTS RESERVED.    |    DEVELOPER BLOG     |