Lurp

Cross-platforn SNP explorer. By Peter D'Adamo, ND


rs12487736

Hard Link
rs12487736 is a snp on gene SCAP (SREBF chaperone)

GeneSCAP Chromosome number 3 Chromosome position 47418189
Alleles C/T Minor Allele T Minor Allele Frequency 0.4523
Notation Clinical significance Orientation (dbSNP) + (positive/forward strand)
Gene Function
This gene encodes a protein with a sterol sensing domain (SSD) and seven WD domains. In the presence of cholesterol, this protein binds to sterol regulatory element binding proteins (SREBPs) and mediates their transport from the ER to the Golgi. The SREBPs are then proteolytically cleaved and regulate sterol biosynthesis. Alternative splicing results in multiple transcript variants.
This SNP is reported by one or more services.


23andme V3

REPORTED




23andme V4

REPORTED




23andme V5

REPORTED




Ancestry DNA

NOT REPORTED




Genos Export for Promethease

REPORTED




DSL/ Opus Chip

REPORTED




Opus 23 Curated

NOT CURATED




CLINVAR Curated

NOT CURATED




GWAS Curated

NOT CURATED





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