Lurp

Cross-platforn SNP explorer. By Peter D'Adamo, ND


rs20541

Hard Link
rs20541 is a snp on gene IL13 (interleukin 13)

GeneIL13 Chromosome number 5 Chromosome position 132660272
Alleles G/A (transliterated to +) Minor Allele A Minor Allele Frequency 0.27
Notation Gln144Arg +2044G/A R130Q Clinical significance Orientation (dbSNP) - (negative/reverse strand)
Gene Function
IL13 is one of a class of immune hormones known as 'cytokines'. IL13 down-regulates the activity of white blood cells known as 'macrophages', and thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. Dietary lectins have been shown to produce immunologic reactions due to their ability to stimulate IL13.
GWAS Pathologies
Self-reported allergy (A) ~ Hodgkin's lymphoma (?) ~ IgE levels (A) ~ Psoriasis (G)
This SNP is reported by one or more services.


23andme V3

REPORTED




23andme V4

REPORTED




23andme V5

REPORTED




Ancestry DNA

REPORTED




Genos Export for Promethease

REPORTED




DSL/ Opus Chip

REPORTED




Opus 23 Curated

CURATED




CLINVAR Curated

CURATED




GWAS Curated

CURATED





MOST RECENT SEARCHES:
rs151264360 (ENOSF1) | rs5742904 (APOB) | rs5853517 (MED12L) | rs2046934 (MED12L) | rs9275572 () | rs4349859 (LOC101929072) | Rs1801131 (MTHFR) | i5000294 (GIF) | rs35829419 (NLRP3) | rs2472553 (CHRNA2) | rs3811450 (CHRNB2)

MOST FREQUENTLY SEARCHED:
rs1799941 (SHBG) | rs9939609 (FTO) | rs1801133 (MTHFR) | rs1801181 (CBS) | rs6025 (F5) | rs20541 (IL13) | rs4680 (COMT) | rs2569191 (CD14) | rs2075252 (LRP2) | rs2235544 (DIO1) | rs2844682 ()








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