Lurp

Cross-platforn SNP explorer. By Peter D'Adamo, ND


rs2069812

Hard Link
rs2069812 is a snp on gene IL5 (interleukin 5 (colony-stimulating factor, eosinophil))

GeneIL5 Chromosome number 5 Chromosome position 132544224
Alleles G/A (transliterated to +) Minor Allele G Minor Allele Frequency 0.4535
Notation Clinical significance Orientation (dbSNP) - (negative/reverse strand)
Gene Function
This gene encodes a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. The encoded cytokine plays a major role in the regulation of eosinophil formation, maturation, recruitment and survival. The increased production of this cytokine may be related to pathogenesis of eosinophil-dependent inflammatory diseases. This cytokine functions by binding to its receptor, which is a heterodimer, whose beta subunit is shared with the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2/GM-CSF). This gene is located on chromosome 5 within a cytokine gene cluster which includes interleukin 4 (IL4), interleukin 13 (IL13), and CSF2 . This gene, IL4, and IL13 may be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31. [provided by RefSeq, Jul 2013]
This SNP is reported by one or more services.


23andme V3

REPORTED




23andme V4

REPORTED




23andme V5

NOT REPORTED




Ancestry DNA

REPORTED




Genos Export for Promethease

NOT REPORTED




DSL/ Opus Chip

REPORTED




Opus 23 Curated

CURATED




CLINVAR Curated

NOT CURATED




GWAS Curated

NOT CURATED





MOST RECENT SEARCHES:
rs1143684 (NQO2) | rs2071002 (LOC105374888) | rs2283725 (MAOA) | rs2129785 (BLMH) | rs686 (DRD1) | rs4532 (DRD1) | rs8192708 (PCK1) | rs2069812 (IL5) | rs1143634 (IL1B) | rs10402876 (C3) | rs104894226 (HRAS)

MOST FREQUENTLY SEARCHED:
rs9939609 (FTO) | rs1799941 (SHBG) | rs1801133 (MTHFR) | rs1801181 (CBS) | rs6025 (F5) | rs20541 (IL13) | rs2569191 (CD14) | rs4680 (COMT) | rs2235544 (DIO1) | rs2075252 (LRP2) | rs2187668 (HLA-DQA1)








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