Lurp

Cross-platforn SNP explorer. By Peter D'Adamo, ND


rs211105

Hard Link
rs211105 is a snp on gene TPH1 (tryptophan hydroxylase 1)

GeneTPH1 Chromosome number 11 Chromosome position 18033757
Alleles G/T Minor Allele G Minor Allele Frequency 0.1538
Notation 302-383A>C A12517C Clinical significance Orientation (dbSNP) + (positive/forward strand)
SNP Function
Intron 3 variant.
Gene Function
The TPH2 gene provides instructions for making a protein that enables the first step in the biosynthesis of serotonin, an important hormone and neurotransmitter. This step is also rate-limiting, which means that any reduction in efficiency of TPH1 will affect the rate of production of serotonin. Variants in this gene have been associated with an increased risk for a variety of diseases and disorders, including schizophrenia, somatic anxiety, anger-related traits, bipolar disorder, suicidal behavior, addictions, and others.
This SNP is reported by one or more services.


23andme V3

REPORTED




23andme V4

REPORTED




23andme V5

NOT REPORTED




Ancestry DNA

REPORTED




Genos Export for Promethease

NOT REPORTED




DSL/ Opus Chip

NOT REPORTED




Opus 23 Curated

CURATED




CLINVAR Curated

NOT CURATED




GWAS Curated

NOT CURATED





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MOST FREQUENTLY SEARCHED:
rs1799941 (SHBG) | rs9939609 (FTO) | rs1801133 (MTHFR) | rs1801181 (CBS) | rs6025 (F5) | rs20541 (IL13) | rs4680 (COMT) | rs2075252 (LRP2) | rs2569191 (CD14) | rs2235544 (DIO1) | rs2844682 ()








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