Hard Linkrs2235544 is a snp on gene
DIO1 (deiodinase, iodothyronine, type I)
Minor Allele Frequency
+ (positive/forward strand)
The DIO1 gene provides instructions for making a protein enzyme called propylthiouracil-sensitive oxidoreductase that activates thyroid hormone by converting the hormone thyroxine (T4), produced in the thyroid, to the active bioactive hormone triiodothyronine (T3). It also degrades both hormones. Some versions of this enzyme contain selenocysteine, a compound based on selenium. DIO1 enzyme has interactions with DIO2, sulfotransferases and glucuronidases in processing, transporting and eliminating hormones and neurotransmitters.