Lurp

Cross-platforn SNP explorer. By Peter D'Adamo, ND


rs27072

Hard Link
rs27072 is a snp on gene SLC6A3 (solute carrier family 6 (neurotransmitter transporter, dopamine), member 3)

GeneSLC6A3 Chromosome number 5 Chromosome position NaN
Alleles T/G/A (transliterated to +) Minor Allele T Minor Allele Frequency 0.2051
Notation *328G>A VNTR Clinical significance Orientation (dbSNP) - (negative/reverse strand)
SNP Function
3'-UTR VNTR is an indication of the number of repeated DNA segments of that gene that can be methylated during oxidative stress involving gene silencing i.e. down regulating gene expression or deacetylated, upregulating gene expression. [http://dx.doi.org/10.1016/j.ygeno.2013.03.003] [PMID: 23517681]
Gene Function
This gene encodes a dopamine transporter which is a member of the sodium- and chloride-dependent neurotransmitter transporter family. The 3' UTR of this gene contains a 40 bp tandem repeat, referred to as a variable number tandem repeat or VNTR, which can be present in 3 to 11 copies. Variation in the number of repeats is associated with idiopathic epilepsy, attention-deficit hyperactivity disorder, dependence on alcohol and cocaine, susceptibility to Parkinson disease and protection against nicotine dependence.
This SNP is reported by one or more services.


23andme V3

REPORTED




23andme V4

REPORTED




23andme V5

REPORTED




Ancestry DNA

REPORTED




Genos Export for Promethease

NOT REPORTED




DSL/ Opus Chip

NOT REPORTED




Opus 23 Curated

CURATED




CLINVAR Curated

NOT CURATED




GWAS Curated

NOT CURATED





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