Lurp

Cross-platforn SNP explorer. By Peter D'Adamo, ND


rs5030728

Hard Link
rs5030728 is a snp on gene TLR4 (toll-like receptor 4)

GeneTLR4 Chromosome number Chromosome position
Alleles (transliterated to +) Minor Allele Minor Allele Frequency
Notation 12823G>A Clinical significance Orientation (dbSNP) - (negative/reverse strand)
SNP Function
The TLR4/rs5030728 intron variant polymorphism has no known functionality.
Gene Function
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
This SNP is reported by one or more services.


23andme V3

NOT REPORTED




23andme V4

NOT REPORTED




23andme V5

REPORTED




Ancestry DNA

REPORTED




Genos Export for Promethease

NOT REPORTED




DSL/ Opus Chip

REPORTED




Opus 23 Curated

CURATED




CLINVAR Curated

NOT CURATED




GWAS Curated

NOT CURATED





MOST RECENT SEARCHES:
rs375021201 () | rs1466785 () | rs2304277 () | rs10127939 () | rs143431368 () | rs860526 (HDC) | rs5030728 () | rs965513 (CHR9-LOC97793827) | rs17235409 () | rs1800668 (GPX1) | rs6316 ()

MOST FREQUENTLY SEARCHED:
rs429358 (APOE) | rs9939609 (FTO) | rs1799941 (SHBG) | rs1801181 (CBS) | rs1801133 (MTHFR) | rs4680 (COMT) | rs6025 (F5) | rs20541 (IL13) | rs2569191 (CD14) | rs2235544 (DIO1) | rs2187668 (HLA-DQA1)








LURP ™ IS A REGISTERED TRADEMARK ® OF DATAPUNK BIOINFORMATICS, LLC. COPYRIGHT © 2015, 2016, 2017, 2018, 2019 ALL RIGHTS RESERVED.    |    DEVELOPER BLOG     |