Fusobacteria

   RANK: Phylum

TAXONOMY: cellular organisms -> Bacteria -> Fusobacteria

OVERVIEW:

Fusobacteria are obligately anaerobic non-sporeforming Gram-negative bacilli. Since the first reports in the late nineteenth century, various names have been applied to these organisms, sometimes with the same name being applied to different species. More recently, not only have there been changes to the nomenclature, but also attempts to differentiate between species which are believed to be either pathogenic or commensal or both. Because of their asaccharolytic nature, and a general paucity of positive results in routine biochemical tests, laboratory identification of the fusobacteria has been difficult. However, the application of novel molecular biological techniques to taxonomy has established a number of new species, together with the subspeciation of Fusobacterium necrophorum and F. nucleatum, and provided new methods for identification. The involvement of fusobacteria in a wide spectrum of human infections causing tissue necrosis and septicaemia has long been recognized, and, more recently, their importance in intra-amniotic infections, premature labour and tropical ulcers has been reported.

Since the first reports of fusobacteria in the late nineteenth century, the variety of species names has led to some confusion within the genera Fusobacterium and Leptotrichia. However, newer methods of investigation have led to a better understanding of the taxonomy, with the description of several new species of fusobacteria. Among the new species described are F. ulcerans from tropical ulcers, and several species from the oral cavity. Subspeciation of the important species F. necrophorum and F. nucleatum has also been possible. It is probable that the taxonomy of the fusobacteria may be further developed in the future.



Microbial Abundance Data: Fusobacteria
(Percent of total population with standard deviation [PMID: 22698087])
Group 1
Group 2
Group 3
Group 4
Group 1 Avg
Buccal
Mucosa
Keratinized
Gingiva
Hard
Palate
Group 2 Avg
Throat
Throat
Tonsils
Saliva
Group 3 Avg
Supragingival
Plaque
Subgingival
Plaque
Stool
3.737 %
(3.813)
3.868 %
(3.557)
2.683 %
(3.987)
4.659 %
(3.896)
10.964 %
(7.489)
10.652 %
(7.895)
14.507 %
(8.740)
11.247 %
(8.660)
7.448 %
(4.662)
13.392 %
(9.203)
11.271 %
(8.955)
15.514 %
(9.452)
0.072 %
(0.500)
TAGS
Keystone Core species Type species Pathogen Dysbiosis associated Flora/ commensal Gut associated Probiotic
Leanness Obesity Skin microbiome Fecal distribution Oral microbiome Vaginal microbiome Butyrate producer Catalase producer
Histamine producer Food fermenter Amylolytic Propionate producer Nitrifying
DESCENDANTS
INTERACTIONS
KEGG PATHWAYS

CLUSTERS WITH
METABOLOMICS       
NUTRIENTS/ SUBSTRATES

ENDPRODUCTS
  • Folate
  • Riboflavin
  • Niacin
  • Vitamin B12

  • INHIBITED BY
  • Whole-grain barley
  • β-Glucan
  • Navy bean (Cooked)

  • ENHANCED BY
  • Sialic acid

  • BIOTRANSFORMS

    BIOTRANFORM
    ANTIBIOTIC RESISTANCE   
    BIOFILM FORMERS   
    COGEM PATHOGENICITY   

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