Datapunk Opus23 | Rothia

Rothia

RANK: Genus

TAXONOMY: Bacteria -> Terrabacteria group -> Actinobacteria -> Actinobacteria -> Micrococcales -> Micrococcaceae -> Rothia

OVERVIEW:

Agenus of bacteria in the family Micrococcaceae. Babies with a higher risk of asthma presented lower levels of four bacteria in their feces samples in comparison with the infants who did not show any symptoms. Those bacteria were identified as Faecalibacterium, Lachnospira, Veillonella and Rothia - known all together as FLVR. [http://www.gutmicrobiotawatch.org/en/2015/11/25/four-types-of-gut-bacteria-may-protect-children-against-asthma-risk/] Identified as constituent of skin microbiome. [PMC2746716]

Coccoid, spherical, dipththeroid, filamentous mycelial cells, usually up to 1.0 µm in diameter. Irregular swellings and clubbed ends up to 5.0 µm in diameter may be present. Growth may be exclusively coccoid, diphtheroid, or filamentous or a mixture of these forms. Gram-stain-positive. Nonmotile. Endospores are absent. Non acid-fast. Mature colonies (4–7 d) 2–6 mm in diameter, usually off-white/cream, smooth or rough, usually soft in texture but may be dry and crumbly or mucoid. Optimum temperature for growth is 30–37°C. Usually catalase-positive. Chemo-organotrophic. Ferments carbohydrates. Major product of glucose fermentation is lactic acid. Does not produce propionic acid. The cell-wall peptidoglycan type is A3α, and contains alanine, glutamic acid, and lysine, but not diaminopimelic acid (DAP). Contains MK-7 as the major isoprenoid quinone. Cell-wall sugars include fructose, galactose, and glucose, but not 6-deoxy-talose or arabinose. DNA G+C content (mol%): 54–60 (Tm) Type species: Rothia dentocariosa

This genus contains microbial species that can reside in the human gastrointestinal tract. [PMC 4262072]

Microbial Abundance Data: Rothia (Percent of total population with standard deviation [PMID: 22698087])
Group 1				Group 2					Group 3			Group 4
Group 1 Avg	Buccal Mucosa	Keratinized Gingiva	Hard Palate	Group 2 Avg	Throat	Throat	Tonsils	Saliva	Group 3 Avg	Supragingival Plaque	Subgingival Plaque	Stool
1.592 % (2.460)	2.277 % (3.858)	0.277 % (0.772)	2.223 % (2.749)	1.284 % (1.845)	1.073 % (1.494)	0.819 % (1.239)	2.243 % (3.064)	1.001 % (1.581)	4.559 % (5.981)	5.444 % (6.814)	3.675 % (5.148)	0.002 % (0.012)

TAGS

Keystone	Core species	Type species	Pathogen	Dysbiosis associated	Flora/ commensal	Gut associated	Probiotic
Leanness	Obesity	Skin microbiome	Fecal distribution	Oral microbiome	Vaginal microbiome	Butyrate producer	Catalase producer
Histamine producer	Food fermenter	Amylolytic	Propionate producer	Nitrifying

DESCENDANTS Rothia aeria Rothia amarae Rothia arfidiae Rothia dentocariosa Rothia endophytica Rothia marina Rothia mucilaginosa Rothia nasimurium Rothia sp. BBH4 Rothia sp. RV13 Rothia sp. THG-N7 Rothia terrae environmental samples	INTERACTIONS	KEGG PATHWAYS 2-Oxocarboxylic acid metabolism ABC transporters Alanine, aspartate and glutamate metabolism Amino sugar and nucleotide sugar metabolism Aminoacyl-tRNA biosynthesis Arginine and proline metabolism Arginine biosynthesis Bacterial secretion system Base excision repair Biosynthesis of amino acids Biosynthesis of antibiotics Biosynthesis of secondary metabolites Biosynthesis of siderophore group nonribosomal peptides Biosynthesis of unsaturated fatty acids Biotin metabolism Butanoate metabolism C5-Branched dibasic acid metabolism Carbon metabolism Chloroalkane and chloroalkene degradation Citrate cycle (TCA cycle) Cyanoamino acid metabolism Cysteine and methionine metabolism D-Alanine metabolism D-Glutamine and D-glutamate metabolism DNA replication Degradation of aromatic compounds Fatty acid biosynthesis Fatty acid degradation Fatty acid metabolism Folate biosynthesis Fructose and mannose metabolism Galactose metabolism Glutathione metabolism Glycerolipid metabolism Glycerophospholipid metabolism Glycine, serine and threonine metabolism Glycolysis / Gluconeogenesis Glyoxylate and dicarboxylate metabolism Histidine metabolism Homologous recombination Insulin resistance Lipoic acid metabolism Lysine biosynthesis Lysine degradation Metabolic pathways Methane metabolism Microbial metabolism in diverse environments Mismatch repair Monobactam biosynthesis Naphthalene degradation Nicotinate and nicotinamide metabolism Nitrogen metabolism Nonribosomal peptide structures Novobiocin biosynthesis Nucleotide excision repair One carbon pool by folate Oxidative phosphorylation Pantothenate and CoA biosynthesis Pentose and glucuronate interconversions Pentose phosphate pathway Peptidoglycan biosynthesis Phenylalanine metabolism Phenylalanine, tyrosine and tryptophan biosynthesis Phosphotransferase system (PTS) Polyketide sugar unit biosynthesis Porphyrin and chlorophyll metabolism Propanoate metabolism Protein export Purine metabolism Pyrimidine metabolism Pyruvate metabolism RNA degradation RNA polymerase Riboflavin metabolism Ribosome Selenocompound metabolism Starch and sucrose metabolism Streptomycin biosynthesis Sulfur metabolism Sulfur relay system Taurine and hypotaurine metabolism Terpenoid backbone biosynthesis Thiamine metabolism Tryptophan metabolism Two-component system Tyrosine metabolism Ubiquinone and other terpenoid-quinone biosynthesis Valine, leucine and isoleucine biosynthesis Valine, leucine and isoleucine degradation Vancomycin resistance Vitamin B6 metabolism beta-Alanine metabolism CLUSTERS WITH	METABOLOMICS NUTRIENTS/ SUBSTRATES D-Glucose Gluten ENDPRODUCTS Lactic acid INHIBITED BY ENHANCED BY Proton-pump inhibitors (PPI) BIOTRANSFORMS BIOTRANFORM
ANTIBIOTIC RESISTANCE Tetracycline (tetw)	BIOFILM FORMERS	COGEM PATHOGENICITY Rothia aeria (2) Rothia dentocariosa (2) Rothia mucilaginosa (2)

OPUS 23™ IS A REGISTERED TRADEMARK ® OF DATAPUNK BIOINFORMATICS, LLC. COPYRIGHT © 2015-2023. ALL RIGHTS RESERVED. |