Aeromonas salmonicida

RANK: Species

TAXONOMY: Bacteria -> Proteobacteria -> Gammaproteobacteria -> Aeromonadales -> Aeromonadaceae -> Aeromonas -> Aeromonas salmonicida

OVERVIEW:

Aeromonas salmonicida subsp. salmonicida is an important pathogen in salmonid aquaculture and is responsible for the typical furunculosis. The type-three secretion system (T3SS) is a major virulence system. In this work, we review structure and function of this highly sophisticated nanosyringe in A. salmonicida. Based on the literature as well as personal experimental observations, we document the genetic (re)organization, expression regulation, anatomy, putative functional origin and roles in the infectious process of this T3SS. We propose a model of pathogenesis where A. salmonicida induces a temporary immunosuppression state in fish in order to acquire free access to host tissues. Finally, we highlight putative important therapeutic and vaccine strategies to prevent furunculosis of salmonid fish.

2

COGEM

COGEM released a comprehensive database of pathogenicity assessment of around 2575 bacterial species in 2011. The database ranks the pathogenicity of species on a scale of 1 to 4. Aeromonas salmonicida ranks 2 on this scale: Species that can cause diseases in humans or animals, which are unlikely to spread in the human population and for which an adequate prophylaxis or therapy exists

TAGS

Keystone	Core species	Type species	Pathogen	Dysbiosis associated	Flora/ commensal	Gut associated	Probiotic
Leanness	Obesity	Skin microbiome	Fecal distribution	Oral microbiome	Vaginal microbiome	Butyrate producer	Catalase producer
Histamine producer	Food fermenter	Amylolytic	Propionate producer	Nitrifying	Biofilm producer

INTERACTIONS	KEGG PATHWAYS CLUSTERS WITH	METABOLOMICS NUTRIENTS/ SUBSTRATES L-Tryptophan ENDPRODUCTS Indole INHIBITED BY Whole-grain barley [parent] β-Glucan [parent] ENHANCED BY Iron [parent] BIOTRANSFORMS BIOTRANFORM
ANTIBIOTIC RESISTANCE See Parent Genus (Aeromonas)	BIOFILM FORMERS See Parent Genus (Aeromonas)	COGEM PATHOGENICITY See Parent Genus (Aeromonas)