Datapunk Opus23 | Eggerthella

Eggerthella

RANK: Genus

TAXONOMY: Bacteria -> Terrabacteria group -> Actinobacteria -> Coriobacteriia -> Eggerthellales -> Eggerthellaceae -> Eggerthella

OVERVIEW:

'Eggerthella' is a bacterial genus of Actinobacteria, in the family Coriobacteriaceae. Members of this genus are anaerobic, non-sporulating, non- motile, Gram-positive bacilli that grow singly, as pairs, or in short chains. They are found in the human colon and feces and have been implicated as a cause of ulcerative colitis, liver and anal abscesses and systemic bacteremia. The type strain for this genus, Eggerthella lenta, was known as Eubacterium lentum prior to 1999. The genus is named for Arnold Eggerth, who first described the organism in 1935.

This genus contains microbial species that can reside in the human gastrointestinal tract. [PMC 4262072] Associated with with increased triglyceride (P=4.1×10−5) and decreased HDL (P=6.3×10−5) [PMID: 26358192]

Microbial Abundance Data: Eggerthella (Percent of total population with standard deviation [PMID: 22698087])
Group 1				Group 2					Group 3			Group 4
Group 1 Avg	Buccal Mucosa	Keratinized Gingiva	Hard Palate	Group 2 Avg	Throat	Throat	Tonsils	Saliva	Group 3 Avg	Supragingival Plaque	Subgingival Plaque	Stool
0.000 % (0.000)	0.000 % (0.000)	0.000 % (0.000)	0.000 % (0.001)	0.000 % (0.000)	0.000 % (0.001)	0.000 % (0.001)	0.000 % (0.000)	0.000 % (0.000)	0.000 % (0.000)	0.000 % (0.000)	0.000 % (0.000)	0.007 % (0.053)

TAGS

Keystone	Core species	Type species	Pathogen	Dysbiosis associated	Flora/ commensal	Gut associated	Probiotic
Leanness	Obesity	Skin microbiome	Fecal distribution	Oral microbiome	Vaginal microbiome	Butyrate producer	Catalase producer
Histamine producer	Food fermenter	Amylolytic	Propionate producer	Nitrifying

DESCENDANTS Eggerthella lenta Eggerthella sinensis Eggerthella sp. 1_3_56FAA Eggerthella sp. E1 Eggerthella sp. HGA1 Eggerthella sp. SDG-2 environmental samples	INTERACTIONS	KEGG PATHWAYS 2-Oxocarboxylic acid metabolism ABC transporters Alanine, aspartate and glutamate metabolism Amino sugar and nucleotide sugar metabolism Aminoacyl-tRNA biosynthesis Arachidonic acid metabolism Arginine and proline metabolism Arginine biosynthesis Bacterial chemotaxis Bacterial secretion system Base excision repair Biosynthesis of amino acids Biosynthesis of antibiotics Biosynthesis of secondary metabolites Biosynthesis of unsaturated fatty acids Biotin metabolism Butanoate metabolism C5-Branched dibasic acid metabolism Carbapenem biosynthesis Carbon metabolism Carotenoid biosynthesis Cationic antimicrobial peptide (CAMP) resistance Chloroalkane and chloroalkene degradation Citrate cycle (TCA cycle) Cyanoamino acid metabolism Cysteine and methionine metabolism D-Alanine metabolism D-Glutamine and D-glutamate metabolism DNA replication Degradation of aromatic compounds Fatty acid biosynthesis Fatty acid degradation Fatty acid metabolism Folate biosynthesis Fructose and mannose metabolism Galactose metabolism Glutathione metabolism Glycerolipid metabolism Glycerophospholipid metabolism Glycine, serine and threonine metabolism Glycolysis / Gluconeogenesis Glyoxylate and dicarboxylate metabolism Histidine metabolism Homologous recombination Lysine biosynthesis Metabolic pathways Methane metabolism Microbial metabolism in diverse environments Mismatch repair Monobactam biosynthesis Naphthalene degradation Nicotinate and nicotinamide metabolism Nitrogen metabolism Nitrotoluene degradation Non-homologous end-joining Novobiocin biosynthesis Nucleotide excision repair One carbon pool by folate Oxidative phosphorylation Pantothenate and CoA biosynthesis Pentose and glucuronate interconversions Pentose phosphate pathway Peptidoglycan biosynthesis Phenylalanine metabolism Phenylalanine, tyrosine and tryptophan biosynthesis Phosphonate and phosphinate metabolism Polyketide sugar unit biosynthesis Porphyrin and chlorophyll metabolism Propanoate metabolism Protein export Purine metabolism Pyrimidine metabolism Pyruvate metabolism RNA degradation RNA polymerase Riboflavin metabolism Ribosome Secondary bile acid biosynthesis Selenocompound metabolism Starch and sucrose metabolism Streptomycin biosynthesis Styrene degradation Sulfur metabolism Sulfur relay system Taurine and hypotaurine metabolism Terpenoid backbone biosynthesis Thiamine metabolism Tryptophan metabolism Two-component system Tyrosine metabolism Ubiquinone and other terpenoid-quinone biosynthesis Valine, leucine and isoleucine biosynthesis Valine, leucine and isoleucine degradation Vancomycin resistance Vitamin B6 metabolism beta-Alanine metabolism beta-Lactam resistance CLUSTERS WITH	METABOLOMICS NUTRIENTS/ SUBSTRATES ENDPRODUCTS INHIBITED BY ENHANCED BY Chemotherapy BIOTRANSFORMS Dihydrodaidzein Daidzein Digoxin BIOTRANFORM Dihydrodigoxin Equol sulphate
ANTIBIOTIC RESISTANCE Vancomycin (vanxb) Vancomycin (vanb) Vancomycin (vanyb) Vancomycin (vanrb) Vancomycin (vansb) Vancomycin (vanhb)	BIOFILM FORMERS	COGEM PATHOGENICITY Eggerthella lenta (2)

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