Ruminococcus

RANK: Genus

TAXONOMY: Bacteria -> Terrabacteria group -> Firmicutes -> Clostridia -> Clostridiales -> Ruminococcaceae -> Ruminococcus

OVERVIEW:

'Ruminococcus' is a genus of bacteria in the class Clostridia. They are anaerobic, Gram-positive gut microbes. One or more species in this genus are found in significant numbers in the intestines of humans. The type species is R. flavefaciens. As usual, bacteria taxonomy is in flux, with Clostridia being paraphyletic, and some erroneous members of Ruminococcus being reassigned to a new genus Blautia on the basis of 16S rRNA gene sequences. Cells are coccoid, usually 0.3–1.5 × 0.7–1.8 µm. Cells are in pairs and chains. A few are motile with 1–3 flagella. Gram-stain-positive cell-wall structure but many stain Gram-negative. Optimal temperature, 37–42°C. Chemo-organotrophic. Strictly anaerobic and require fermentable carbohydrates to grow. Fermentation of carbohydrate yields various proportions of acetate, formate, succinate, lactate, and ethanol. Amino acid and peptides are not fermented. Indole is not produced (Bryant, 1986). Isolated from rumen, large bowel, or cecum of many animals and humans. Some are isolated from human clinical specimens. Rumen fluid agar is effective to isolate and characterize strains (Holdeman et al., 1977). Some strains use cellulose on rumen fluid cellobiose agar plate (Holdeman et al., 1977) and require ammonia as a nitrogen source.

This genus contains microbial species that can reside in the human gastrointestinal tract. [PMC 4262072]

Blood group A-degrading activity; blood group H-degrading activity (R. torques). Blood group B-degrading activity; blood group H-degrading activity (R. gnavus) [PMC 4365749]


Gut associated
Flora/ commensal
Beta Galactosidase
Fecal distribution
Microbial Abundance Data: Ruminococcus
Percent of total population with standard deviation [PMID: 22698087]. Percentages > 1% highlighted.
Buccal
Mucosa
Keratinized
Gingiva
Hard
Palate
Throat
Tonsils
Saliva
Stool
0.003 %
(0.012)
0.001 %
(0.005)
0.008 %
(0.028)
0.021 %
(0.156)
0.000 %
(0.003)
0.005 %
(0.023)
1.624 %
(2.894)
Name
Rank
Client %
Avg %
Avg StdDev
Client StdDev
Ruminococcus
genus
4.45
1.624
2.894
WNL >30%
DESCENDANTS
INTERACTIONS
Ruminococcus enhances growth of
  • Anaerostipes
  • Bacteroidales
  • Bacteroides
  • Odoribacter
  • Peptococcaceae

  • Ruminococcus inhibits growth of
  • Adlercreutzia
  • Bifidobacterium
  • Blautia
  • Campylobacteraceae
  • Clostridiales Family XIII. Incertae Sedis
  • Clostridiales incertae sedis
  • Clostridium
  • Collinsella
  • Coprococcus
  • Coriobacteriales
  • Dialister
  • Dorea
  • Erysipelotrichaceae
  • Lachnospiraceae
  • Porphyromonas
  • Prevotella
  • Ruminococcaceae
  • Ruminococcus

  • Ruminococcus growth inhibited by
  • Acetivibrio
  • Acidaminococcus
  • Adlercreutzia
  • Akkermansia
  • Alcaligenaceae
  • Alistipes
  • Bacteroidales
  • Bacteroides
  • Bifidobacterium
  • Bilophila
  • Blautia
  • Campylobacteraceae
  • Catabacteriaceae
  • Clostridiales
  • Clostridiales Family XIII. Incertae Sedis
  • Clostridiales incertae sedis
  • Clostridium
  • Collinsella
  • Coprococcus
  • Coriobacteriales
  • Desulfovibrio
  • Dialister
  • Dorea
  • Enterobacteriaceae
  • Erysipelotrichaceae
  • Escherichia
  • Eubacterium
  • Faecalibacterium
  • Holdemania
  • Lachnobacterium
  • Lachnospira
  • Lachnospiraceae
  • Odoribacter
  • Oscillospira
  • Oxalobacter
  • Parabacteroides
  • Peptococcaceae
  • Peptoniphilus
  • Phascolarctobacterium
  • Porphyromonadaceae
  • Porphyromonas
  • Prevotella
  • Rikenellaceae
  • Roseburia
  • Rubrivivax
  • Ruminiclostridium
  • Ruminococcaceae
  • Ruminococcus
  • Streptococcus
  • Turicibacter
  • Veillonella
  • METABOLOMICS   

    Metabolic Endproducts
  • Ethanol
  • Lactate
  • Succinate
  • Acetate
  • Formate

  • Growth Inhibited by
  • Proton-pump inhibitors (PPI)
  • Momordia charantia
  • High fat diet
  • Flaxseed
  • Gallate [parent]
  • High meat diet

  • Growth Enhanced By
  • Black Beans
  • β-Glucan
  • Resistant starch (type II)
  • Saccharomyces boulardii [parent]
  • Quercetin w. Resveratrol [parent]
  • Gynostemma pentaphyllum
  • Resistant starch (type IV)
  • Walnuts [parent]
  • Whole-grain barley
  • Saccharomyces boulardii
  • Berberine [parent]
  • Navy bean (Cooked)

  • Biotransforms
  • Trimethylamine
  • Ginsenoside Rb1

  • Transform Product
  • Trimethylamine-N-oxide (TMAO)

  • Antibiotic Resistance
  • Vancomycin (vanrd)
  • Teicoplanin (vanrd)
  • Vancomycin (vansd)
  • Teicoplanin (vansd)
  • Vancomycin (vand)
  • Teicoplanin (vand)
  • Vancomycin (vanb)
  • Vancomycin (vanxd)
  • Teicoplanin (vanxd)
  • Vancomycin (vanhd)
  • Teicoplanin (vanhd)
  • Vancomycin (vanyd)
  • Teicoplanin (vanyd)