Escherichia: Polymyxin resistance


Polymyxin description

23S rRNA of 50S ribosomal subunit, protein synthesis inhibitor

Basic polypeptide antibiotic group obtained from Bacillus polymyxa. They affect the cell membrane by detergent action and may cause neuromuscular and kidney damage. At least eleven different members of the polymyxin group have been identified, each designated by a letter.

Polymyxin resistance gene: arna