Bacillus: Tunicamycin resistance


Tunicamycin description

23S rRNA of 50S ribosomal subunit, protein synthesis inhibitor

An N-acetylglycosamine containing antiviral antibiotic obtained from Streptomyces lysosuperificus. It is also active against some bacteria and fungi, because it inhibits the glucosylation of proteins. Tunicamycin is used as tool in the study of microbial biosynthetic mechanisms.

Tunicamycin resistance gene: tmrb