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Ruminococcus

RANK: Genus

TAXONOMY: Bacteria -> Terrabacteria group -> Firmicutes -> Clostridia -> Clostridiales -> Ruminococcaceae -> Ruminococcus

OVERVIEW:

'Ruminococcus' is a genus of bacteria in the class Clostridia. They are anaerobic, Gram-positive gut microbes. One or more species in this genus are found in significant numbers in the intestines of humans. The type species is R. flavefaciens. As usual, bacteria taxonomy is in flux, with Clostridia being paraphyletic, and some erroneous members of Ruminococcus being reassigned to a new genus Blautia on the basis of 16S rRNA gene sequences. Cells are coccoid, usually 0.3–1.5 × 0.7–1.8 µm. Cells are in pairs and chains. A few are motile with 1–3 flagella. Gram-stain-positive cell-wall structure but many stain Gram-negative. Optimal temperature, 37–42°C. Chemo-organotrophic. Strictly anaerobic and require fermentable carbohydrates to grow. Fermentation of carbohydrate yields various proportions of acetate, formate, succinate, lactate, and ethanol. Amino acid and peptides are not fermented. Indole is not produced (Bryant, 1986). Isolated from rumen, large bowel, or cecum of many animals and humans. Some are isolated from human clinical specimens. Rumen fluid agar is effective to isolate and characterize strains (Holdeman et al., 1977). Some strains use cellulose on rumen fluid cellobiose agar plate (Holdeman et al., 1977) and require ammonia as a nitrogen source.

This genus contains microbial species that can reside in the human gastrointestinal tract. [PMC 4262072]

Blood group A-degrading activity; blood group H-degrading activity (R. torques). Blood group B-degrading activity; blood group H-degrading activity (R. gnavus) [PMC 4365749]



Microbial Abundance Data: Ruminococcus
(Percent of total population with standard deviation [PMID: 22698087])
Group 1
Group 2
Group 3
Group 4
Group 1 Avg
Buccal
Mucosa
Keratinized
Gingiva
Hard
Palate
Group 2 Avg
Throat
Throat
Tonsils
Saliva
Group 3 Avg
Supragingival
Plaque
Subgingival
Plaque
Stool
0.004 %
(0.015)
0.003 %
(0.012)
0.001 %
(0.005)
0.008 %
(0.028)
0.007 %
(0.049)
0.021 %
(0.156)
0.003 %
(0.014)
0.000 %
(0.003)
0.005 %
(0.023)
0.001 %
(0.010)
0.000 %
(0.002)
0.002 %
(0.018)
1.624 %
(2.894)
TAGS
Keystone
Core species
Type species
Pathogen
Dysbiosis associated
Flora/ commensal
Gut associated
Probiotic
Leanness
Obesity
Skin microbiome
Fecal distribution
Oral microbiome
Vaginal microbiome
Butyrate producer
Catalase producer
Histamine producer
Food fermenter
Amylolytic
Propionate producer
Nitrifying
Biofilm producer
DESCENDANTS
INTERACTIONS
ENHANCES
  • Anaerostipes
  • Bacteroidales
  • Bacteroides
  • Odoribacter
  • Peptococcaceae
  • Bacteroidales
  • Bacteroides
  • Odoribacter
  • Anaerostipes
  • Peptococcaceae

  • INHIBITS
  • Bifidobacterium
  • Coriobacteriales
  • Adlercreutzia
  • Collinsella
  • Porphyromonas
  • Prevotella
  • Clostridium
  • Clostridiales incertae sedis
  • Clostridiales Family XIII. Incertae Sedis
  • Blautia
  • Coprococcus
  • Dorea
  • Lachnospiraceae
  • Ruminococcaceae
  • Ruminococcus
  • Dialister
  • Campylobacteraceae
  • Erysipelotrichaceae
  • Bifidobacterium
  • Coriobacteriales
  • Adlercreutzia
  • Collinsella
  • Porphyromonas
  • Prevotella
  • Clostridium
  • Clostridiales incertae sedis
  • Clostridiales Family XIII. Incertae Sedis
  • Blautia
  • Coprococcus
  • Dorea
  • Lachnospiraceae
  • Ruminococcaceae
  • Ruminococcus
  • Dialister
  • Campylobacteraceae
  • Erysipelotrichaceae

  • INHIBITED BY
  • Bifidobacterium
  • Bifidobacterium
  • Coriobacteriales
  • Coriobacteriales
  • Adlercreutzia
  • Adlercreutzia
  • Collinsella
  • Collinsella
  • Bacteroidales
  • Bacteroidales
  • Bacteroides
  • Bacteroides
  • Porphyromonadaceae
  • Porphyromonadaceae
  • Odoribacter
  • Odoribacter
  • Parabacteroides
  • Parabacteroides
  • Porphyromonas
  • Porphyromonas
  • Prevotella
  • Prevotella
  • Rikenellaceae
  • Rikenellaceae
  • Alistipes
  • Alistipes
  • Turicibacter
  • Turicibacter
  • Streptococcus
  • Streptococcus
  • Clostridiales
  • Clostridiales
  • Catabacteriaceae
  • Catabacteriaceae
  • Clostridium
  • Clostridium
  • Clostridiales incertae sedis
  • Clostridiales incertae sedis
  • Peptoniphilus
  • Peptoniphilus
  • Clostridiales Family XIII. Incertae Sedis
  • Clostridiales Family XIII. Incertae Sedis
  • Lachnospiraceae
  • Lachnospiraceae
  • Blautia
  • Blautia
  • Lachnospiraceae
  • Lachnospiraceae
  • Coprococcus
  • Coprococcus
  • Dorea
  • Dorea
  • Eubacterium
  • Eubacterium
  • Lachnobacterium
  • Lachnobacterium
  • Lachnospira
  • Lachnospira
  • Roseburia
  • Roseburia
  • Lachnospiraceae
  • Lachnospiraceae
  • Peptococcaceae
  • Peptococcaceae
  • Ruminococcaceae
  • Ruminococcaceae
  • Ruminiclostridium
  • Ruminiclostridium
  • Acetivibrio
  • Acetivibrio
  • Eubacterium
  • Eubacterium
  • Faecalibacterium
  • Faecalibacterium
  • Oscillospira
  • Oscillospira
  • Ruminococcus
  • Ruminococcus
  • Acidaminococcus
  • Acidaminococcus
  • Dialister
  • Dialister
  • Phascolarctobacterium
  • Phascolarctobacterium
  • Veillonella
  • Veillonella
  • Rubrivivax
  • Rubrivivax
  • Alcaligenaceae
  • Alcaligenaceae
  • Oxalobacter
  • Oxalobacter
  • Bilophila
  • Bilophila
  • Desulfovibrio
  • Desulfovibrio
  • Campylobacteraceae
  • Campylobacteraceae
  • Enterobacteriaceae
  • Enterobacteriaceae
  • Escherichia
  • Escherichia
  • Erysipelotrichaceae
  • Erysipelotrichaceae
  • Erysipelotrichaceae
  • Erysipelotrichaceae
  • Holdemania
  • Holdemania
  • Akkermansia
  • Akkermansia
  • KEGG PATHWAYS
  • 2-Oxocarboxylic acid metabolism
  • ABC transporters
  • Alanine, aspartate and glutamate metabolism
  • Amino sugar and nucleotide sugar metabolism
  • Aminoacyl-tRNA biosynthesis
  • Arachidonic acid metabolism
  • Arginine and proline metabolism
  • Arginine biosynthesis
  • Bacterial chemotaxis
  • Bacterial secretion system
  • Base excision repair
  • Benzoate degradation
  • Biosynthesis of amino acids
  • Biosynthesis of antibiotics
  • Biosynthesis of secondary metabolites
  • Biosynthesis of siderophore group nonribosomal peptides
  • Biosynthesis of unsaturated fatty acids
  • Biotin metabolism
  • Butanoate metabolism
  • C5-Branched dibasic acid metabolism
  • Carbapenem biosynthesis
  • Carbon metabolism
  • Cationic antimicrobial peptide (CAMP) resistance
  • Chloroalkane and chloroalkene degradation
  • Citrate cycle (TCA cycle)
  • Cyanoamino acid metabolism
  • Cysteine and methionine metabolism
  • D-Alanine metabolism
  • D-Glutamine and D-glutamate metabolism
  • DNA replication
  • Degradation of aromatic compounds
  • Fatty acid biosynthesis
  • Fatty acid degradation
  • Fatty acid metabolism
  • Folate biosynthesis
  • Fructose and mannose metabolism
  • Galactose metabolism
  • Glutathione metabolism
  • Glycerolipid metabolism
  • Glycerophospholipid metabolism
  • Glycine, serine and threonine metabolism
  • Glycolysis / Gluconeogenesis
  • Glyoxylate and dicarboxylate metabolism
  • Histidine metabolism
  • Homologous recombination
  • Inositol phosphate metabolism
  • Insulin resistance
  • Lysine biosynthesis
  • Metabolic pathways
  • Methane metabolism
  • Microbial metabolism in diverse environments
  • Mismatch repair
  • Monobactam biosynthesis
  • Naphthalene degradation
  • Nicotinate and nicotinamide metabolism
  • Nitrogen metabolism
  • Novobiocin biosynthesis
  • Nucleotide excision repair
  • One carbon pool by folate
  • Other glycan degradation
  • Oxidative phosphorylation
  • Pantothenate and CoA biosynthesis
  • Pentose and glucuronate interconversions
  • Pentose phosphate pathway
  • Peptidoglycan biosynthesis
  • Phenylalanine metabolism
  • Phenylalanine, tyrosine and tryptophan biosynthesis
  • Phosphonate and phosphinate metabolism
  • Phosphotransferase system (PTS)
  • Polyketide sugar unit biosynthesis
  • Porphyrin and chlorophyll metabolism
  • Propanoate metabolism
  • Protein export
  • Purine metabolism
  • Pyrimidine metabolism
  • Pyruvate metabolism
  • RNA degradation
  • RNA polymerase
  • Riboflavin metabolism
  • Ribosome
  • Selenocompound metabolism
  • Sphingolipid metabolism
  • Starch and sucrose metabolism
  • Streptomycin biosynthesis
  • Sulfur metabolism
  • Sulfur relay system
  • Taurine and hypotaurine metabolism
  • Terpenoid backbone biosynthesis
  • Thiamine metabolism
  • Tryptophan metabolism
  • Two-component system
  • Tyrosine metabolism
  • Valine, leucine and isoleucine biosynthesis
  • Valine, leucine and isoleucine degradation
  • Vancomycin resistance
  • Vitamin B6 metabolism
  • beta-Alanine metabolism
  • beta-Lactam resistance

  • CLUSTERS WITH
    METABOLOMICS       
    NUTRIENTS/ SUBSTRATES

    ENDPRODUCTS
  • Ethanol
  • Lactate
  • Succinate
  • Acetate
  • Formate
  • ANTIBIOTIC RESISTANCE   BIOFILM FORMERS   
    COGEM PATHOGENICITY   

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