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Peptoniphilus

RANK: Genus

TAXONOMY: Bacteria -> Terrabacteria group -> Firmicutes -> Tissierellia -> Tissierellales -> Peptoniphilaceae -> Peptoniphilus

OVERVIEW:

The name Peptoniphilus derives from: 'friend of peptone', referring to the use of peptone as a major energy source. Peptoniphilus are gram positive anaerobic cocci that were formerly classified in the genus Peptostreptococcus. They are non-saccharolytic, use peptone as a major energy source and produce butyrate.This genus is part of the vaginal and gut microbiota. They have been reported to as present in diabetic skin and soft tissue infections, bone and joint infections, surgical site infections, chorioamnionitis and bloodstream infections. They are typically found as part of polymicrobial infections but are difficult to recover with usual clinical cultures. They have been increasingly reported with the more widespread use of 16S PCR and MALDI-TOF for identification. Peptoniphilus spp. are Gram-positive anaerobic cocci (GPAC) that were formerly classified in the genus Peptostreptococcus. Non-spore-forming, obligately anaerobic, Gram-stain-positive, cocci. Cells may occur in pairs, short chains, tetrads, or small masses. Nonmotile. Optimal growth temperature is 37°C. The major metabolic end product from peptone yeast extract glucose (PYG) medium is butyric acid. Carbohydrates are not fermented. Use peptones and oligopeptide as major energy source. The position 1, position 3, and interpeptide bridge of peptidoglycan are alanine, l-ornithine, and d-glutamic acid (Li et al., 1992; Schleifer and Nimmermann, 1973; Weiss, 1981). DNA G+C content (mol%): 25–34 (Ezaki, 1982).

Type species: Peptoniphilus asaccharolyticus

This genus contains microbial species that can reside in the human gastrointestinal tract. [PMC 4262072]



Microbial Abundance Data: Peptoniphilus
(Percent of total population with standard deviation [PMID: 22698087])
Group 1
Group 2
Group 3
Group 4
Group 1 Avg
Buccal
Mucosa
Keratinized
Gingiva
Hard
Palate
Group 2 Avg
Throat
Throat
Tonsils
Saliva
Group 3 Avg
Supragingival
Plaque
Subgingival
Plaque
Stool
0.001 %
(0.005)
0.001 %
(0.006)
0.000 %
(0.000)
0.001 %
(0.009)
0.004 %
(0.034)
0.001 %
(0.008)
0.010 %
(0.062)
0.000 %
(0.003)
0.005 %
(0.062)
0.000 %
(0.003)
0.000 %
(0.000)
0.001 %
(0.006)
0.002 %
(0.016)
TAGS
Keystone
Core species
Type species
Pathogen
Dysbiosis associated
Flora/ commensal
Gut associated
Probiotic
Leanness
Obesity
Skin microbiome
Fecal distribution
Oral microbiome
Vaginal microbiome
Butyrate producer
Catalase producer
Histamine producer
Food fermenter
Amylolytic
Propionate producer
Nitrifying
Biofilm producer
DESCENDANTS
  • Candidatus Peptoniphilus massiliensis
  • Peptoniphilus asaccharolyticus
  • Peptoniphilus catoniae
  • Peptoniphilus coxii
  • Peptoniphilus duerdenii
  • Peptoniphilus gorbachii
  • Peptoniphilus grossensis
  • Peptoniphilus harei
  • Peptoniphilus indolicus
  • Peptoniphilus ivorii
  • Peptoniphilus koenoeneniae
  • Peptoniphilus lacrimalis
  • Peptoniphilus methioninivorax
  • Peptoniphilus obesi
  • Peptoniphilus olsenii
  • Peptoniphilus rhinitidis
  • Peptoniphilus senegalensis
  • Peptoniphilus sp. 1-14
  • Peptoniphilus sp. 2002-2300004
  • Peptoniphilus sp. 2002-38328
  • Peptoniphilus sp. 7-2
  • Peptoniphilus sp. BV3AC2
  • Peptoniphilus sp. DNF00192
  • Peptoniphilus sp. JCM 8143
  • Peptoniphilus sp. S4-13
  • Peptoniphilus sp. S4-14
  • Peptoniphilus sp. S4-A10
  • Peptoniphilus sp. S7MS8
  • Peptoniphilus sp. S9 PR-13
  • Peptoniphilus sp. gpac018A
  • Peptoniphilus sp. gpac148
  • Peptoniphilus sp. oral taxon 375
  • Peptoniphilus sp. oral taxon 836
  • Peptoniphilus stercorisuis
  • Peptoniphilus timonensis
  • Peptoniphilus tyrrelliae
  • environmental samples
  • INTERACTIONS
    KEGG PATHWAYS

    CLUSTERS WITH
    METABOLOMICS       
    NUTRIENTS/ SUBSTRATES
  • Peptone

  • ENDPRODUCTS
  • Butyrate
  • ANTIBIOTIC RESISTANCE   
    BIOFILM FORMERS   COGEM PATHOGENICITY   

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