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Nocardia

RANK: Genus

TAXONOMY: Bacteria -> Terrabacteria group -> Actinobacteria -> Actinobacteria -> Corynebacteriales -> Nocardiaceae -> Nocardia

OVERVIEW:

Nocardia is a genus of weakly staining Gram-positive, catalase-positive, rod-shaped bacteria. It forms partially acid-fast beaded branching filaments (acting as fungi, but being truly bacteria). It contains a total of 85 species. Some species are nonpathogenic, while others are responsible for nocardiosis. Nocardia species are found worldwide in soil rich in organic matter. In addition, they are oral microflora found in healthy gingiva, as well as periodontal pockets. Most Nocardia infections are acquired by inhalation of the bacteria or through traumatic introduction. Nocardia asteroides is most frequently found species infecting humans, and most cases occur as an opportunistic infection in immunocompromised patients. Other species of medical interest are N. brasiliensis and N. caviae. Because it is acid-fast to some degree, it stains only weakly Gram positive.

The most common form of human nocardial disease is a slowly progressive pneumonia, the common symptoms of which include cough, dyspnea (shortness of breath), and fever. It is not uncommon for this infection to spread to the pleura or chest wall. Pre-existing pulmonary disease, especially pulmonary alveolar proteinosis, increases the risk of contracting a Nocardia pneumonia. Every organ can be affected if a systemic spread takes place.



TAGS
Keystone
Core species
Type species
Pathogen
Dysbiosis associated
Flora/ commensal
Gut associated
Probiotic
Leanness
Obesity
Skin microbiome
Fecal distribution
Oral microbiome
Vaginal microbiome
Butyrate producer
Catalase producer
Histamine producer
Food fermenter
Amylolytic
Propionate producer
Nitrifying
Biofilm producer
DESCENDANTS
  • Nocardia abscessus
  • Nocardia aciditolerans
  • Nocardia acidivorans
  • Nocardia africana
  • Nocardia alba
  • Nocardia alboflava
  • Nocardia altamirensis
  • Nocardia amamiensis
  • Nocardia amikacinitolerans
  • Nocardia anaemiae
  • Nocardia aobensis
  • Nocardia araoensis
  • Nocardia argentinensis
  • Nocardia artemisiae
  • Nocardia arthritidis
  • Nocardia asiatica
  • Nocardia asteroides
  • Nocardia beijingensis
  • Nocardia bhagyanarayanae
  • Nocardia blacklockiae
  • Nocardia brasiliensis
  • Nocardia brevicatena
  • Nocardia caishijiensis
  • Nocardia callitridis
  • Nocardia camponoti
  • Nocardia canicruria
  • Nocardia carnea
  • Nocardia casuarinae
  • Nocardia caverna
  • Nocardia cerradoensis
  • Nocardia coeliaca
  • Nocardia concava
  • Nocardia coubleae
  • Nocardia crassostreae
  • Nocardia cummidelens
  • Nocardia cyriacigeorgica
  • Nocardia devorans
  • Nocardia elegans
  • Nocardia endophytica
  • Nocardia exalbida
  • Nocardia farcinica
  • Nocardia flavorosea
  • Nocardia fluminea
  • Nocardia fusca
  • Nocardia gamkensis
  • Nocardia globerula
  • Nocardia goodfellowii
  • Nocardia grenadensis
  • Nocardia halotolerans
  • Nocardia harenae
  • Nocardia higoensis
  • Nocardia ignorata
  • Nocardia inohanensis
  • Nocardia interforma
  • Nocardia iowensis
  • Nocardia jejuensis
  • Nocardia jiangxiensis
  • Nocardia jinanensis
  • Nocardia kroppenstedtii
  • Nocardia kruczakiae
  • Nocardia levis
  • Nocardia lijiangensis
  • Nocardia lillensis
  • Nocardia mexicana
  • Nocardia mikamii
  • Nocardia miyunensis
  • Nocardia neocaledoniensis
  • Nocardia niigatensis
  • Nocardia ninae
  • Nocardia niwae
  • Nocardia nova
  • Nocardia novocastrensa
  • Nocardia otitidiscaviarum
  • Nocardia paucivorans
  • Nocardia pigrifrangens
  • Nocardia pneumoniae
  • Nocardia polyresistens
  • Nocardia pseudobrasiliensis
  • Nocardia pseudosporangifera
  • Nocardia pseudovaccinii
  • Nocardia puris
  • Nocardia rayongensis
  • Nocardia rhamnosiphila
  • Nocardia roseoalba
  • Nocardia salmonicida
  • Nocardia salmonicolor
  • Nocardia seriolae
  • Nocardia shimofusensis
  • Nocardia sienata
  • Nocardia soli
  • Nocardia sp.
  • Nocardia speluncae
  • Nocardia strombolensis
  • Nocardia sungurluensis
  • Nocardia sylvodorifera
  • Nocardia takedensis
  • Nocardia tartaricans
  • Nocardia tenerifensis
  • Nocardia terpenica
  • Nocardia testacea
  • Nocardia thailandica
  • Nocardia thraciensis
  • Nocardia transvalensis
  • Nocardia uniformis
  • Nocardia vaccinii
  • Nocardia vermiculata
  • Nocardia veterana
  • Nocardia vinacea
  • Nocardia violaceofusca
  • Nocardia vulneris
  • Nocardia wallacei
  • Nocardia xishanensis
  • Nocardia yamanashiensis
  • environmental samples
  • INTERACTIONS
    KEGG PATHWAYS
  • 2-Oxocarboxylic acid metabolism
  • ABC transporters
  • Acarbose and validamycin biosynthesis
  • Alanine, aspartate and glutamate metabolism
  • Amino sugar and nucleotide sugar metabolism
  • Aminoacyl-tRNA biosynthesis
  • Aminobenzoate degradation
  • Arachidonic acid metabolism
  • Arginine and proline metabolism
  • Arginine biosynthesis
  • Ascorbate and aldarate metabolism
  • Atrazine degradation
  • Bacterial secretion system
  • Base excision repair
  • Benzoate degradation
  • Biosynthesis of amino acids
  • Biosynthesis of ansamycins
  • Biosynthesis of antibiotics
  • Biosynthesis of enediyne antibiotics
  • Biosynthesis of secondary metabolites
  • Biosynthesis of siderophore group nonribosomal peptides
  • Biosynthesis of type II polyketide backbone
  • Biosynthesis of type II polyketide products
  • Biosynthesis of unsaturated fatty acids
  • Biosynthesis of vancomycin group antibiotics
  • Biotin metabolism
  • Butanoate metabolism
  • C5-Branched dibasic acid metabolism
  • Caprolactam degradation
  • Carbapenem biosynthesis
  • Carbon fixation in photosynthetic organisms
  • Carbon metabolism
  • Carotenoid biosynthesis
  • Cationic antimicrobial peptide (CAMP) resistance
  • Chloroalkane and chloroalkene degradation
  • Chlorocyclohexane and chlorobenzene degradation
  • Citrate cycle (TCA cycle)
  • Cyanoamino acid metabolism
  • Cysteine and methionine metabolism
  • D-Alanine metabolism
  • D-Arginine and D-ornithine metabolism
  • D-Glutamine and D-glutamate metabolism
  • DNA replication
  • Degradation of aromatic compounds
  • Dioxin degradation
  • Ether lipid metabolism
  • Fatty acid biosynthesis
  • Fatty acid degradation
  • Fatty acid metabolism
  • Fluorobenzoate degradation
  • Folate biosynthesis
  • Fructose and mannose metabolism
  • Galactose metabolism
  • Geraniol degradation
  • Glutathione metabolism
  • Glycerolipid metabolism
  • Glycerophospholipid metabolism
  • Glycine, serine and threonine metabolism
  • Glycolysis / Gluconeogenesis
  • Glyoxylate and dicarboxylate metabolism
  • Histidine metabolism
  • Homologous recombination
  • Inositol phosphate metabolism
  • Limonene and pinene degradation
  • Lipoic acid metabolism
  • Lysine biosynthesis
  • Lysine degradation
  • Metabolic pathways
  • Methane metabolism
  • Microbial metabolism in diverse environments
  • Mismatch repair
  • Monobactam biosynthesis
  • Naphthalene degradation
  • Nicotinate and nicotinamide metabolism
  • Nitrogen metabolism
  • Nitrotoluene degradation
  • Non-homologous end-joining
  • Novobiocin biosynthesis
  • Nucleotide excision repair
  • One carbon pool by folate
  • Other glycan degradation
  • Oxidative phosphorylation
  • Pantothenate and CoA biosynthesis
  • Penicillin and cephalosporin biosynthesis
  • Pentose and glucuronate interconversions
  • Pentose phosphate pathway
  • Peptidoglycan biosynthesis
  • Phenazine biosynthesis
  • Phenylalanine metabolism
  • Phenylalanine, tyrosine and tryptophan biosynthesis
  • Phosphonate and phosphinate metabolism
  • Polyketide sugar unit biosynthesis
  • Porphyrin and chlorophyll metabolism
  • Propanoate metabolism
  • Proteasome
  • Protein export
  • Purine metabolism
  • Pyrimidine metabolism
  • Pyruvate metabolism
  • Quorum sensing00253
  • RNA degradation
  • RNA polymerase
  • Riboflavin metabolism
  • Ribosome
  • Secondary bile acid biosynthesis
  • Selenocompound metabolism
  • Sesquiterpenoid and triterpenoid biosynthesis
  • Sphingolipid metabolism
  • Starch and sucrose metabolism
  • Staurosporine biosynthesis
  • Steroid biosynthesis
  • Steroid degradation
  • Streptomycin biosynthesis
  • Styrene degradation
  • Sulfur metabolism
  • Sulfur relay system
  • Synthesis and degradation of ketone bodies
  • Taurine and hypotaurine metabolism
  • Terpenoid backbone biosynthesis
  • Tetracycline biosynthesis
  • Thiamine metabolism
  • Toluene degradation
  • Tryptophan metabolism
  • Two-component system
  • Tyrosine metabolism
  • Ubiquinone and other terpenoid-quinone biosynthesis
  • Valine, leucine and isoleucine biosynthesis
  • Valine, leucine and isoleucine degradation
  • Vancomycin resistance
  • Vitamin B6 metabolism
  • Xylene degradation
  • alpha-Linolenic acid metabolism
  • beta-Alanine metabolism
  • beta-Lactam resistance

  • CLUSTERS WITH
    METABOLOMICS       
    NUTRIENTS/ SUBSTRATES
  • Urea

  • ENDPRODUCTS
  • Ammonia
  • ANTIBIOTIC RESISTANCE   
    BIOFILM FORMERS   COGEM PATHOGENICITY   

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