The Lachnospiraceae are one of the most abundant families from the order Clostridiales found in the mammalian gut environment, and have been associated with the maintenance of gut health. Many members of this family are butyrate producers. A study done in Norway in 2014, found significant correlations between bacteria in stool samples and depression, with elevated levels of the order Bacteroidales and a reduced abundance of the family Lachnospiraceae.
Both secretor status and blood group antigen expression especially affect the Lachnospiraceae family of bacteria within the gut microbiome, with lower abundances noted in nonsecretors and higher abundances in secretors of various blood groups. [PMCID: PMC5625272]
Lachnospiraceae were found to be enhanced in formula-fed infants compared with solely breastfed infants. [PMID: 29868719]
Microbial Abundance Data: Lachnospiraceae (Percent of total population with standard deviation [PMID: 22698087])