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Campylobacter jejuni

RANK: Species

TAXONOMY: Proteobacteria -> delta/epsilon subdivisions -> Epsilonproteobacteria -> Campylobacterales -> Campylobacteraceae -> Campylobacter -> Campylobacter jejuni

OVERVIEW:

Campylobacter jejuni is a species of bacterium commonly found in animal feces. It is curved, helical-shaped, non-spore forming, Gram-negative, and microaerophilic. This species of pathogenic bacteria is one of the most common causes of human gastroenteritis in the world. Food poisoning caused by Campylobacter species can be severely debilitating, but is rarely life-threatening. It has been linked with subsequent development of Guillain–Barré syndrome (GBS), which usually develops two to three weeks after the initial illness. Infection with C. jejuni usually results in enteritis, which is characterised by abdominal pain, diarrhea, fever, and malaise. The onset of symptoms is usually 2-5 days. The symptoms usually persist for between 24 hours and a week, but may be longer. Diarrhea can vary in severity from loose stools to bloody stools. Dehydration is a common concern. Many fluids and electrolytes are lost through vomiting and diarrhea. Dehydration is very common in the young as well as in the elderly. People who are taking diuretics are also at risk for dehydration. Caffeine should be avoided as this increases urine output. The use of probiotics is recommended in order to maintain healthy bacteria within the digestive system. The disease is usually self-limiting. However, it does respond to antibiotics. Severe (accompanying fevers, blood in stools) or prolonged cases may require erythromycin, azithromycin, ciprofloxacin, or norfloxacin. Fluid and electrolyte replacement may be required for serious cases.

This species has been identified as a resident in the human gastrointestinal tract based on the phylogenetic framework of its small subunit ribosomal RNA gene sequences.[PMC 4262072]

2

COGEM
COGEM released a comprehensive database of pathogenicity assessment of around 2575 bacterial species in 2011. The database ranks the pathogenicity of species on a scale of 1 to 4. Campylobacter jejuni ranks 2 on this scale: Species that can cause diseases in humans or animals, which are unlikely to spread in the human population and for which an adequate prophylaxis or therapy exists


TAGS >
Keystone
Core species
Type species
Pathogen
Dysbiosis associated
Flora/ commensal
Gut associated
Probiotic
Leanness
Obesity
Skin microbiome
Fecal distribution
Oral microbiome
Vaginal microbiome
Butyrate producer
Catalase producer
Histamine producer
Food fermenter
Amylolytic
Propionate producer
Nitrifying
Biofilm producer
INTERACTIONS
KEGG PATHWAYS

CLUSTERS WITH
METABOLOMICS       
NUTRIENTS/ SUBSTRATES
  • Catecholamines

  • ENDPRODUCTS
    ANTIBIOTIC RESISTANCE   BIOFILM FORMERS   COGEM PATHOGENICITY   

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