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Faecalibacterium

RANK: Genus

TAXONOMY: Bacteria -> Terrabacteria group -> Firmicutes -> Clostridia -> Clostridiales -> Ruminococcaceae -> Faecalibacterium

OVERVIEW:

'Faecalibacterium' is a genus of bacteria. Its sole known species, 'Faecalibacterium prausnitzii', is an important commensal bacterium of the human gut flora. This bacteria is considered beneficial and is one of the most prevalent intestinal bacterial species in healthy adults. The reduction of this bacteria in the gut (as measured by analyzing bacteria in fecal samples) is seen in several diseases, including Intestinal Bowel Disease (IBD). This bacteria has also been found to be anti-inflammatory. Babies with a higher risk of asthma presented lower levels of four bacteria in their feces samples in comparison with the infants who did not show any symptoms. Those bacteria were identified as Faecalibacterium, Lachnospira, Veillonella and Rothia - known all together as FLVR. A high animal meat, high animal fat, high sugar, highly processed foods, and low fiber diet (the typical westernized diet) lowers F. prausnitzii numbers, while a high-fiber, low meat diet increases F. prausnitzii numbers.Scientists at Catholic University of Louvain in Belgium recently showed that adding inulin, a fermentable fiber, to the diet of obese women increased counts of F. prausnitzii and other clostridial bacteria.

This genus contains microbial species that can reside in the human gastrointestinal tract. [PMC 4262072] Decrease in metabolic disorders.

Microbial Abundance Data: Faecalibacterium
(Percent of total population with standard deviation [PMID: 22698087])
Group 1
Group 2
Group 3
Group 4
Group 1 Avg
Buccal
Mucosa
Keratinized
Gingiva
Hard
Palate
Group 2 Avg
Throat
Throat
Tonsils
Saliva
Group 3 Avg
Supragingival
Plaque
Subgingival
Plaque
Stool
0.015 %
(0.073)
0.007 %
(0.021)
0.003 %
(0.013)
0.035 %
(0.185)
0.012 %
(0.065)
0.027 %
(0.151)
0.011 %
(0.071)
0.001 %
(0.005)
0.009 %
(0.032)
0.005 %
(0.035)
0.000 %
(0.003)
0.009 %
(0.067)
4.580 %
(5.185)
TAGS
Keystone Core species Type species Pathogen Dysbiosis associated Flora/ commensal Gut associated Probiotic
Leanness Obesity Skin microbiome Fecal distribution Oral microbiome Vaginal microbiome Butyrate producer Catalase producer
Histamine producer Food fermenter Amylolytic Propionate producer Nitrifying
DESCENDANTS
INTERACTIONS
ENHANCES
  • Roseburia
  • Anaerostipes
  • Bacteroidales
  • Bacteroides
  • Odoribacter
  • Peptococcaceae
  • Bacteroidales
  • Bacteroides
  • Odoribacter
  • Peptococcaceae

  • INHIBITS
  • Alistipes
  • Bifidobacterium
  • Coriobacteriales
  • Adlercreutzia
  • Collinsella
  • Porphyromonas
  • Prevotella
  • Clostridium
  • Clostridiales incertae sedis
  • Clostridiales Family XIII. Incertae Sedis
  • Blautia
  • Coprococcus
  • Dorea
  • Lachnospiraceae
  • Ruminococcaceae
  • Ruminococcus
  • Dialister
  • Campylobacteraceae
  • Erysipelotrichaceae
  • Bifidobacterium
  • Coriobacteriales
  • Adlercreutzia
  • Collinsella
  • Porphyromonas
  • Prevotella
  • Clostridium
  • Clostridiales incertae sedis
  • Clostridiales Family XIII. Incertae Sedis
  • Blautia
  • Coprococcus
  • Dorea
  • Lachnospiraceae
  • Ruminococcaceae
  • Ruminococcus
  • Dialister
  • Campylobacteraceae
  • Erysipelotrichaceae

  • INHIBITED BY
  • Bifidobacterium
  • Coriobacteriales
  • Adlercreutzia
  • Collinsella
  • Bacteroidales
  • Bacteroides
  • Porphyromonadaceae
  • Odoribacter
  • Parabacteroides
  • Porphyromonas
  • Prevotella
  • Rikenellaceae
  • Alistipes
  • Turicibacter
  • Streptococcus
  • Clostridiales
  • Catabacteriaceae
  • Clostridium
  • Clostridiales incertae sedis
  • Peptoniphilus
  • Clostridiales Family XIII. Incertae Sedis
  • Lachnospiraceae
  • Blautia
  • Lachnospiraceae
  • Coprococcus
  • Dorea
  • Eubacterium
  • Lachnobacterium
  • Lachnospira
  • Roseburia
  • Lachnospiraceae
  • Peptococcaceae
  • Ruminococcaceae
  • Ruminiclostridium
  • Acetivibrio
  • Eubacterium
  • Faecalibacterium
  • Oscillospira
  • Ruminococcus
  • Acidaminococcus
  • Dialister
  • Phascolarctobacterium
  • Veillonella
  • Rubrivivax
  • Alcaligenaceae
  • Oxalobacter
  • Bilophila
  • Desulfovibrio
  • Campylobacteraceae
  • Enterobacteriaceae
  • Escherichia
  • Erysipelotrichaceae
  • Erysipelotrichaceae
  • Holdemania
  • Akkermansia
  • KEGG PATHWAYS
  • 2-Oxocarboxylic acid metabolism
  • ABC transporters
  • Alanine, aspartate and glutamate metabolism
  • Amino sugar and nucleotide sugar metabolism
  • Aminoacyl-tRNA biosynthesis
  • Arginine and proline metabolism
  • Arginine biosynthesis
  • Bacterial secretion system
  • Base excision repair
  • Benzoate degradation
  • Biosynthesis of amino acids
  • Biosynthesis of antibiotics
  • Biosynthesis of secondary metabolites
  • Biosynthesis of unsaturated fatty acids
  • Biotin metabolism
  • Butanoate metabolism
  • C5-Branched dibasic acid metabolism
  • Carbapenem biosynthesis
  • Carbon metabolism
  • Citrate cycle (TCA cycle)
  • Cyanoamino acid metabolism
  • Cysteine and methionine metabolism
  • D-Alanine metabolism
  • D-Glutamine and D-glutamate metabolism
  • DNA replication
  • Fatty acid biosynthesis
  • Fatty acid degradation
  • Fatty acid metabolism
  • Folate biosynthesis
  • Fructose and mannose metabolism
  • Galactose metabolism
  • Glutathione metabolism
  • Glycerolipid metabolism
  • Glycerophospholipid metabolism
  • Glycine, serine and threonine metabolism
  • Glycolysis / Gluconeogenesis
  • Glyoxylate and dicarboxylate metabolism
  • Histidine metabolism
  • Homologous recombination
  • Inositol phosphate metabolism
  • Insulin resistance
  • Lysine biosynthesis
  • Lysine degradation
  • Metabolic pathways
  • Methane metabolism
  • Microbial metabolism in diverse environments
  • Mismatch repair
  • Monobactam biosynthesis
  • Nicotinate and nicotinamide metabolism
  • Nitrogen metabolism
  • Novobiocin biosynthesis
  • Nucleotide excision repair
  • One carbon pool by folate
  • Other glycan degradation
  • Oxidative phosphorylation
  • Pantothenate and CoA biosynthesis
  • Pentose and glucuronate interconversions
  • Pentose phosphate pathway
  • Peptidoglycan biosynthesis
  • Phenylalanine metabolism
  • Phenylalanine, tyrosine and tryptophan biosynthesis
  • Phosphotransferase system (PTS)
  • Polyketide sugar unit biosynthesis
  • Porphyrin and chlorophyll metabolism
  • Propanoate metabolism
  • Protein export
  • Purine metabolism
  • Pyrimidine metabolism
  • Pyruvate metabolism
  • RNA degradation
  • RNA polymerase
  • Riboflavin metabolism
  • Ribosome
  • Selenocompound metabolism
  • Starch and sucrose metabolism
  • Streptomycin biosynthesis
  • Sulfur metabolism
  • Sulfur relay system
  • Synthesis and degradation of ketone bodies
  • Taurine and hypotaurine metabolism
  • Terpenoid backbone biosynthesis
  • Thiamine metabolism
  • Two-component system
  • Valine, leucine and isoleucine biosynthesis
  • Valine, leucine and isoleucine degradation
  • Vancomycin resistance
  • Vitamin B6 metabolism
  • beta-Lactam resistance

  • CLUSTERS WITH
    METABOLOMICS       
    NUTRIENTS/ SUBSTRATES
  • Raffinose
  • D-Glucose
  • Galacturonic acid
  • Riboflavin
  • Arabinogalactan
  • Stachyose (soy oligosaccharide)
  • N-Acetyl-D-glucosamine
  • Inulin
  • Acetate
  • Pectin

  • ENDPRODUCTS
  • D-lactate
  • Butyrate
  • Formate

  • INHIBITED BY
  • Chemotherapy
  • High sugar diet
  • High fat diet
  • High animal protein diet
  • Gallate [parent]
  • Omega 3 fatty acids
  • Fructo-oligosaccharides
  • Bile salts
  • Resistant starch (type IV)
  • High animal fat diet
  • Low fiber diet
  • Low FODMAP diet
  • Flaxseed
  • High processed foods diet
  • Navy bean (Cooked)

  • ENHANCED BY
  • Fasting
  • Epinephrine
  • Resistant starch (type III)
  • Jerusalem artichoke
  • Saccharomyces boulardii [parent]
  • Red wine
  • Arabinogalactan
  • Low animal protein diet
  • Walnuts [parent]
  • Low processed foods diet
  • Chicory
  • Inulin
  • High fiber diet
  • Berberine [parent]
  • Dopamine

  • BIOTRANSFORMS

    BIOTRANFORM

    ANTIBIOTIC RESISTANCE
  • Tetracycline (tetw)

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