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Burkholderia

RANK: Genus

TAXONOMY: cellular organisms -> Bacteria -> Proteobacteria -> Betaproteobacteria -> Burkholderiales -> Burkholderiaceae -> Burkholderia

OVERVIEW:

'Burkholderia' is a genus of Proteobacteria whose pathogenic members include Burkholderia mallei, responsible for glanders, a disease that occurs mostly in horses and related animals; Burkholderia pseudomallei, causative agent of melioidosis; and Burkholderia cepacia, an important pathogen of pulmonary infections in people with cystic fibrosis (CF). The Burkholderia (previously part of Pseudomonas) genus name refers to a group of virtually ubiquitous Gram-negative, motile, obligately aerobic rod- shaped bacteria including both animal and plant pathogens, as well as some environmentally important species. In particular, B. xenovorans (previously named Pseudomonas cepacia then B. cepacia and B. fungorum) is renowned for being catalase positive (affecting patients with chronic granulomatous disease) and its ability to degrade chlororganic pesticides and polychlorinated biphenyls (PCBs). The use of Burkholderia species for agricultural purposes (such as biodegradation, biocontrol, and plant growth-promoting rhizobacteria) is subject to discussions because of possible pathogenic effects in immunocompromised people (especially cystic fibrosis-sufferers), e.g., hospital-acquired infections. However, the animal pathogenic and the plant/soil species belong to different groups, and it was proposed to separate them into two different genera, to avoid misinterpretations. Due to their antibiotic resistance and the high mortality rate from their associated diseases, Burkholderia mallei B. mallei and Burkholderia pseudomallei B. pseudomallei are considered to be potential biological warfare agents, targeting livestock and humans. The genus was named after Walter H. Burkholder, plant pathologist at Cornell University.



Microbial Abundance Data: Burkholderia
(Percent of total population with standard deviation [PMID: 22698087])
Group 1
Group 2
Group 3
Group 4
Group 1 Avg
Buccal
Mucosa
Keratinized
Gingiva
Hard
Palate
Group 2 Avg
Throat
Throat
Tonsils
Saliva
Group 3 Avg
Supragingival
Plaque
Subgingival
Plaque
Stool
0.000 %
(0.002)
0.000 %
(0.002)
0.000 %
(0.000)
0.001 %
(0.004)
0.001 %
(0.017)
0.005 %
(0.061)
0.001 %
(0.003)
0.000 %
(0.000)
0.000 %
(0.004)
0.000 %
(0.002)
0.000 %
(0.002)
0.000 %
(0.002)
0.000 %
(0.000)
TAGS
Keystone
Core species
Type species
Pathogen
Dysbiosis associated
Flora/ commensal
Gut associated
Probiotic
Leanness
Obesity
Skin microbiome
Fecal distribution
Oral microbiome
Vaginal microbiome
Butyrate producer
Catalase producer
Histamine producer
Food fermenter
Amylolytic
Propionate producer
Nitrifying
Biofilm producer
DESCENDANTS
  • 'Burkholderia humi' Srinivasan et al. 2013
  • Burkholderia B_22
  • Burkholderia acidipaludis
  • Burkholderia andropogonis
  • Burkholderia aspalathi
  • Burkholderia australis
  • Burkholderia bannensis
  • Burkholderia bryophila
  • Burkholderia caballeronis
  • Burkholderia caledonica
  • Burkholderia caribensis
  • Burkholderia caryophylli
  • Burkholderia cepacia complex
  • Burkholderia choica
  • Burkholderia cordobensis
  • Burkholderia dabaoshanensis
  • Burkholderia denitrificans
  • Burkholderia diazotrophica
  • Burkholderia dilworthii
  • Burkholderia dipogonis
  • Burkholderia eburnea
  • Burkholderia endofungorum
  • Burkholderia ferrariae
  • Burkholderia fungorum
  • Burkholderia ginsengisoli
  • Burkholderia gladioli
  • Burkholderia glathei
  • Burkholderia glumae
  • Burkholderia graminis
  • Burkholderia grimmiae
  • Burkholderia heleia
  • Burkholderia hospita
  • Burkholderia humi Vandamme et al. 2013
  • Burkholderia insulsa
  • Burkholderia jiangsuensis
  • Burkholderia kirstenboschensis
  • Burkholderia kururiensis
  • Burkholderia megalochromosomata
  • Burkholderia megapolitana
  • Burkholderia mimosarum
  • Burkholderia monticola
  • Burkholderia nodosa
  • Burkholderia oxyphila
  • Burkholderia phenazinium
  • Burkholderia phenoliruptrix
  • Burkholderia phymatum
  • Burkholderia phytofirmans
  • Burkholderia plantarii
  • Burkholderia rhizoxinica
  • Burkholderia rhynchosiae
  • Burkholderia rinojensis
  • Burkholderia sabiae
  • Burkholderia sacchari
  • Burkholderia sartisoli
  • Burkholderia sediminicola
  • Burkholderia silvatlantica
  • Burkholderia singaporensis
  • Burkholderia soli
  • Burkholderia sordidicola
  • Burkholderia sp.
  • Burkholderia sp. CBPB-HIM
  • Burkholderia sprentiae
  • Burkholderia susongensis
  • Burkholderia symbiont of Asellus aquaticus
  • Burkholderia symbiont of Cavelerius saccharivorus
  • Burkholderia symbiotica
  • Burkholderia telluris
  • Burkholderia terrae
  • Burkholderia terrestris
  • Burkholderia terricola
  • Burkholderia tropica
  • Burkholderia tuberum
  • Burkholderia ubonensis
  • Burkholderia udeis
  • Burkholderia unamae
  • Burkholderia xenovorans
  • Burkholderia zhejiangensis
  • Candidatus Burkholderia brachyanthoides
  • Candidatus Burkholderia calva
  • Candidatus Burkholderia crenata
  • Candidatus Burkholderia hispidae
  • Candidatus Burkholderia humilis
  • Candidatus Burkholderia kirkii
  • Candidatus Burkholderia mamillata
  • Candidatus Burkholderia nigropunctata
  • Candidatus Burkholderia pumila
  • Candidatus Burkholderia rigidae
  • Candidatus Burkholderia schumannianae
  • Candidatus Burkholderia verschuerenii
  • Candidatus Burkholderia virens
  • Candidatus Vallotia cooleyia
  • Candidatus Vallotia tarda
  • Candidatus Vallotia virida
  • [Pseudomonas] jianii
  • environmental samples
  • pseudomallei group
  • INTERACTIONS
    KEGG PATHWAYS
  • 2-Oxocarboxylic acid metabolism
  • ABC transporters
  • Alanine, aspartate and glutamate metabolism
  • Amino sugar and nucleotide sugar metabolism
  • Aminoacyl-tRNA biosynthesis
  • Aminobenzoate degradation
  • Arachidonic acid metabolism
  • Arginine and proline metabolism
  • Arginine biosynthesis
  • Ascorbate and aldarate metabolism
  • Atrazine degradation
  • Bacterial chemotaxis
  • Bacterial secretion system
  • Base excision repair
  • Benzoate degradation
  • Biosynthesis of amino acids
  • Biosynthesis of antibiotics
  • Biosynthesis of secondary metabolites
  • Biosynthesis of unsaturated fatty acids
  • Biosynthesis of vancomycin group antibiotics
  • Biotin metabolism
  • Butanoate metabolism
  • C5-Branched dibasic acid metabolism
  • Caprolactam degradation
  • Carbapenem biosynthesis
  • Carbon fixation in photosynthetic organisms
  • Carbon metabolism
  • Carotenoid biosynthesis
  • Cationic antimicrobial peptide (CAMP) resistance
  • Chloroalkane and chloroalkene degradation
  • Chlorocyclohexane and chlorobenzene degradation
  • Citrate cycle (TCA cycle)
  • Cyanoamino acid metabolism
  • Cysteine and methionine metabolism
  • D-Alanine metabolism
  • D-Arginine and D-ornithine metabolism
  • D-Glutamine and D-glutamate metabolism
  • DNA replication
  • Degradation of aromatic compounds
  • Dioxin degradation
  • Ethylbenzene degradation
  • Fatty acid biosynthesis
  • Fatty acid degradation
  • Fatty acid metabolism
  • Flagellar assembly
  • Fluorobenzoate degradation
  • Folate biosynthesis
  • Fructose and mannose metabolism
  • Galactose metabolism
  • Geraniol degradation
  • Glutathione metabolism
  • Glycerolipid metabolism
  • Glycerophospholipid metabolism
  • Glycine, serine and threonine metabolism
  • Glycolysis / Gluconeogenesis
  • Glyoxylate and dicarboxylate metabolism
  • Histidine metabolism
  • Homologous recombination
  • Inositol phosphate metabolism
  • Insulin resistance
  • Limonene and pinene degradation
  • Lipoic acid metabolism
  • Lipopolysaccharide biosynthesis
  • Lysine biosynthesis
  • Lysine degradation
  • Metabolic pathways
  • Methane metabolism
  • Microbial metabolism in diverse environments
  • Mismatch repair
  • Monobactam biosynthesis
  • Naphthalene degradation
  • Nicotinate and nicotinamide metabolism
  • Nitrogen metabolism
  • Non-homologous end-joining
  • Nonribosomal peptide structures
  • Novobiocin biosynthesis
  • Nucleotide excision repair
  • One carbon pool by folate
  • Oxidative phosphorylation
  • Pantothenate and CoA biosynthesis
  • Penicillin and cephalosporin biosynthesis
  • Pentose and glucuronate interconversions
  • Pentose phosphate pathway
  • Peptidoglycan biosynthesis
  • Phenylalanine metabolism
  • Phenylalanine, tyrosine and tryptophan biosynthesis
  • Phosphonate and phosphinate metabolism
  • Phosphotransferase system (PTS)
  • Polycyclic aromatic hydrocarbon degradation
  • Polyketide sugar unit biosynthesis
  • Porphyrin and chlorophyll metabolism
  • Propanoate metabolism
  • Protein export
  • Purine metabolism
  • Pyrimidine metabolism
  • Pyruvate metabolism
  • RNA degradation
  • RNA polymerase
  • Riboflavin metabolism
  • Ribosome
  • Selenocompound metabolism
  • Sesquiterpenoid and triterpenoid biosynthesis
  • Starch and sucrose metabolism
  • Steroid biosynthesis
  • Streptomycin biosynthesis
  • Styrene degradation
  • Sulfur metabolism
  • Sulfur relay system
  • Synthesis and degradation of ketone bodies
  • Taurine and hypotaurine metabolism
  • Terpenoid backbone biosynthesis
  • Thiamine metabolism
  • Toluene degradation
  • Tryptophan metabolism
  • Two-component system
  • Tyrosine metabolism
  • Ubiquinone and other terpenoid-quinone biosynthesis
  • Valine, leucine and isoleucine biosynthesis
  • Valine, leucine and isoleucine degradation
  • Vancomycin resistance
  • Vitamin B6 metabolism
  • Xylene degradation
  • alpha-Linolenic acid metabolism
  • beta-Alanine metabolism
  • beta-Lactam resistance

  • CLUSTERS WITH
    Group 124
  • Burkholderia
  • Burkholderia cepacia
  • Group 11
  • Xanthobacter autotrophicus
  • Nocardioides
  • Pseudomonas syringae
  • Arthrobacter
  • Pseudomonas mendocina
  • Rhodococcus
  • Ralstonia eutropha
  • Burkholderia cepacia
  • Mycobacterium
  • Acinetobacter
  • Alcanivorax borkumensis
  • Burkholderia
  • Bdellovibrio bacteriovorus
  • Polaromonas naphthalenivorans
  • Vibrio fischeri
  • Acidovorax
  • Pseudomonas aeruginosa
  • Pseudomonas putida
  • Pseudomonas fluorescens
  • Caulobacter crescentus
  • Serratia proteamaculans
  • Group 1
  • Mesorhizobium loti
  • Acidovorax avenae
  • Cupriavidus necator
  • Burkholderia cepacia
  • Shigella flexneri
  • Rhizobium etli
  • Brucella melitensis
  • Xanthomonas campestris
  • Rhizobium leguminosarum
  • Agrobacterium tumefaciens
  • Erwinia carotovora
  • Ralstonia solanacearum
  • Caulobacter crescentus
  • Bartonella tribocorum
  • Xylella fastidiosa
  • Sinorhizobium meliloti
  • Burkholderia pseudomallei
  • Gloeobacter violaceus
  • Ochrobactrum anthropi
  • Clavibacter michiganensis
  • Pseudomonas syringae
  • Xanthomonas oryzae
  • Bradyrhizobium japonicum
  • Acinetobacter
  • Burkholderia
  • Bartonella bacilliformis
  • Burkholderia cenocepacia
  • Cupriavidus metallidurans
  • Vibrio fischeri
  • Xanthomonas axonopodis
  • Brucella suis
  • Chromobacterium violaceum
  • Group 37
  • Burkholderia
  • Burkholderia vietnamiensis
  • Azoarcus
  • Parvibaculum lavamentivorans
  • Burkholderia cenocepacia
  • Arthrobacter
  • Acidovorax
  • Rhodococcus
  • Mesorhizobium
  • Sphingomonas wittichii
  • Marinomonas
  • Acinetobacter
  • Group 188
  • Ralstonia eutropha
  • Burkholderia
  • METABOLOMICS       
    NUTRIENTS/ SUBSTRATES

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