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Enterobacter cloacae

RANK: Species

TAXONOMY: Bacteria -> Proteobacteria -> Gammaproteobacteria -> Enterobacteriales -> Enterobacteriaceae -> Enterobacter -> Enterobacter cloacae

OVERVIEW:

Enterobacter cloacae is a clinically significant Gram-negative, facultatively-anaerobic, rod-shaped bacterium. In microbiology labs, E. cloacae is frequently grown at 30 °C on nutrient agar or broth or at 35 °C in tryptic soy broth. It is a rod-shaped, Gram-negative bacterium, is facultatively anaerobic, and bears peritrichous flagella. It is oxidase-negative and catalase-positive. Enterobacter cloacae is ornithine decarboxylase positive. Enterobacter cloacae is a member of the normal gut flora of many humans and is not usually a primary pathogen. It is sometimes associated with urinary tract and respiratory tract infections. Treatment with cefepime and gentamicin has been reported.

A 2012 study in which Enterobacter cloacae transplanted into previously germ-free mice resulted in increased obesity when compared with germ-free mice fed an identical diet, suggesting a link between obesity and the presence of Enterobacter gut flora.

This species has been identified as a resident in the human gastrointestinal tract based on the phylogenetic framework of its small subunit ribosomal RNA gene sequences.[PMC 4262072]

2

COGEM
COGEM released a comprehensive database of pathogenicity assessment of around 2575 bacterial species in 2011. The database ranks the pathogenicity of species on a scale of 1 to 4. Enterobacter cloacae ranks 2 on this scale: Species that can cause diseases in humans or animals, which are unlikely to spread in the human population and for which an adequate prophylaxis or therapy exists


TAGS >
Keystone
Core species
Type species
Pathogen
Dysbiosis associated
Flora/ commensal
Gut associated
Probiotic
Leanness
Obesity
Skin microbiome
Fecal distribution
Oral microbiome
Vaginal microbiome
Butyrate producer
Catalase producer
Histamine producer
Food fermenter
Amylolytic
Propionate producer
Nitrifying
Biofilm producer
INTERACTIONS
ENHANCES
  • Pseudomonas
  • KEGG PATHWAYS

    CLUSTERS WITH
    Group 192 [Obesity]
  • Enterobacter cloacae
  • METABOLOMICS       
    ANTIBIOTIC RESISTANCE   BIOFILM FORMERS   COGEM PATHOGENICITY   

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