SUBSTRATA MAIN PAGE


Shigella

RANK: Genus

TAXONOMY: cellular organisms -> Bacteria -> Proteobacteria -> Gammaproteobacteria -> Enterobacteriales -> Enterobacteriaceae -> Shigella

OVERVIEW:

Straight rods, 1–3 × 0.7–1.0 µm, that conform to the general definition of the family Enterobacteriaceae and contain the enterobacterial common antigen. Gram negative. Nonmotile. Non-pigmented. Facultatively anaerobic, having both a respiratory and a fermentative type of metabolism. Catalase positive (with exceptions in Shigella dysenteriae). Oxidase negative. Chemoorganotrophic. Ferment sugars without gas production (a few exceptions produce gas). Salicin, adonitol, and myo-inositol are not fermented. Strains of Shigella sonnei ferment lactose and sucrose upon extended incubation; however, other species do not utilize these substances in conventional medium. Do not utilize citrate, malonate, or sodium acetate (with exceptions in Shigella flexneri for sodium acetate) as a sole carbon source. Do not grow in KCN or produce H2S. Do not decarboxylate lysine. Reduce nitrates to nitrites. Intestinal pathogens of humans and other primates, causing bacillary dysentery. Based on 16S rDNA sequencing, shigellae belong in the Gammaproteobacteria.The mol% G + C of the DNA is: 49–53 (Laskin and Lechevalier, 1981).Type species: Shigella dysenteriae

This genus contains microbial species that can reside in the human gastrointestinal tract. [PMC 4262072]



Microbial Abundance Data: Shigella
(Percent of total population with standard deviation [PMID: 22698087])
Group 1
Group 2
Group 3
Group 4
Group 1 Avg
Buccal
Mucosa
Keratinized
Gingiva
Hard
Palate
Group 2 Avg
Throat
Throat
Tonsils
Saliva
Group 3 Avg
Supragingival
Plaque
Subgingival
Plaque
Stool
0.004 %
(0.018)
0.005 %
(0.022)
0.001 %
(0.007)
0.007 %
(0.025)
0.006 %
(0.047)
0.007 %
(0.022)
0.001 %
(0.007)
0.000 %
(0.000)
0.016 %
(0.158)
0.002 %
(0.020)
0.000 %
(0.002)
0.004 %
(0.038)
0.100 %
(0.665)
TAGS
Keystone
Core species
Type species
Pathogen
Dysbiosis associated
Flora/ commensal
Gut associated
Probiotic
Leanness
Obesity
Skin microbiome
Fecal distribution
Oral microbiome
Vaginal microbiome
Butyrate producer
Catalase producer
Histamine producer
Food fermenter
Amylolytic
Propionate producer
Nitrifying
Biofilm producer
DESCENDANTS
INTERACTIONS
KEGG PATHWAYS
  • 2-Oxocarboxylic acid metabolism
  • ABC transporters
  • Alanine, aspartate and glutamate metabolism
  • Amino sugar and nucleotide sugar metabolism
  • Aminoacyl-tRNA biosynthesis
  • Aminobenzoate degradation
  • Arachidonic acid metabolism
  • Arginine and proline metabolism
  • Arginine biosynthesis
  • Ascorbate and aldarate metabolism
  • Bacterial chemotaxis
  • Bacterial invasion of epithelial cells
  • Bacterial secretion system
  • Base excision repair
  • Benzoate degradation
  • Biosynthesis of amino acids
  • Biosynthesis of antibiotics
  • Biosynthesis of secondary metabolites
  • Biosynthesis of siderophore group nonribosomal peptides
  • Biosynthesis of unsaturated fatty acids
  • Biotin metabolism
  • Butanoate metabolism
  • C5-Branched dibasic acid metabolism
  • Caprolactam degradation
  • Carbapenem biosynthesis
  • Carbon metabolism
  • Cationic antimicrobial peptide (CAMP) resistance
  • Chloroalkane and chloroalkene degradation
  • Chlorocyclohexane and chlorobenzene degradation
  • Citrate cycle (TCA cycle)
  • Cyanoamino acid metabolism
  • Cysteine and methionine metabolism
  • D-Alanine metabolism
  • D-Glutamine and D-glutamate metabolism
  • DNA replication
  • Degradation of aromatic compounds
  • Ether lipid metabolism
  • Fatty acid biosynthesis
  • Fatty acid degradation
  • Fatty acid metabolism
  • Flagellar assembly
  • Fluorobenzoate degradation
  • Folate biosynthesis
  • Fructose and mannose metabolism
  • Galactose metabolism
  • Geraniol degradation
  • Glutathione metabolism
  • Glycerolipid metabolism
  • Glycerophospholipid metabolism
  • Glycine, serine and threonine metabolism
  • Glycolysis / Gluconeogenesis
  • Glyoxylate and dicarboxylate metabolism
  • Histidine metabolism
  • Homologous recombination
  • Inositol phosphate metabolism
  • Insulin resistance
  • Limonene and pinene degradation
  • Lipoic acid metabolism
  • Lipopolysaccharide biosynthesis
  • Lysine biosynthesis
  • Lysine degradation
  • Metabolic pathways
  • Methane metabolism
  • Microbial metabolism in diverse environments
  • Mismatch repair
  • Monobactam biosynthesis
  • Naphthalene degradation
  • Nicotinate and nicotinamide metabolism
  • Nitrogen metabolism
  • Nitrotoluene degradation
  • Novobiocin biosynthesis
  • Nucleotide excision repair
  • One carbon pool by folate
  • Other glycan degradation
  • Oxidative phosphorylation
  • Pantothenate and CoA biosynthesis
  • Pentose and glucuronate interconversions
  • Pentose phosphate pathway
  • Peptidoglycan biosynthesis
  • Phenylalanine metabolism
  • Phenylalanine, tyrosine and tryptophan biosynthesis
  • Phosphotransferase system (PTS)
  • Polyketide sugar unit biosynthesis
  • Porphyrin and chlorophyll metabolism
  • Propanoate metabolism
  • Protein export
  • Purine metabolism
  • Pyrimidine metabolism
  • Pyruvate metabolism
  • RNA degradation
  • RNA polymerase
  • Riboflavin metabolism
  • Ribosome
  • Selenocompound metabolism
  • Shigellosis
  • Starch and sucrose metabolism
  • Streptomycin biosynthesis
  • Sulfur metabolism
  • Sulfur relay system
  • Taurine and hypotaurine metabolism
  • Terpenoid backbone biosynthesis
  • Thiamine metabolism
  • Toluene degradation
  • Tryptophan metabolism
  • Two-component system
  • Tyrosine metabolism
  • Ubiquinone and other terpenoid-quinone biosynthesis
  • Valine, leucine and isoleucine biosynthesis
  • Valine, leucine and isoleucine degradation
  • Vancomycin resistance
  • Vitamin B6 metabolism
  • alpha-Linolenic acid metabolism
  • beta-Alanine metabolism
  • beta-Lactam resistance

  • CLUSTERS WITH
    METABOLOMICS       
    ANTIBIOTIC RESISTANCE   
  • Aminoglycoside (acrb)
  • Glycylcycline (acrb)
  • Macrolide (acrb)
  • Beta lactam (acrb)
  • Acriflavin (acrb)
  • Macrolide (mpha)
  • Chloramphenicol (cata1)
  • Paromomycin (aph3ia)
  • Neomycin (aph3ia)
  • Kanamycin (aph3ia)
  • Ribostamycin (aph3ia)
  • Lividomycin (aph3ia)
  • Gentamincin b (aph3ia)
  • Cloxacillin (bl2d_oxa10)
  • Penicillin (bl2d_oxa10)
  • Tetracycline (tetd)
  • Fosmidomycin (rosa)
  • Polymyxin (arna)
  • Sulfonamide (sul1)
  • T chloride (mdtn)
  • Acriflavine (mdtn)
  • Puromycin (mdtn)
  • Trimethoprim (dfra7)
  • Chloramphenicol (mdtm)
  • Acriflavine (mdtm)
  • Norfloxacin (mdtm)
  • Monobactam (bl2be_shv2)
  • E cephalosproin (bl2be_shv2)
  • Penicillin (bl2be_shv2)
  • N cephalosproin (bl2be_shv2)
  • Spectinomycin (ant3ia)
  • Streptomycin (ant3ia)
  • Doxorubicin (mdtf)
  • Erythromycin (mdtf)
  • Tobramycin (aac6ia)
  • Netilmicin (aac6ia)
  • Isepamicin (aac6ia)
  • Amikacin (aac6ia)
  • Sisomicin (aac6ia)
  • Dibekacin (aac6ia)
  • Tobramycin (aac6ib)
  • Netilmicin (aac6ib)
  • Isepamicin (aac6ib)
  • Amikacin (aac6ib)
  • Sisomicin (aac6ib)
  • Dibekacin (aac6ib)
  • Deoxycholate (mdth)
  • Fosfomycin (mdth)
  • Tobramycin (ant2ia)
  • Sisomicin (ant2ia)
  • Kanamycin (ant2ia)
  • Gentamicin (ant2ia)
  • Dibekacin (ant2ia)
  • Bacitracin (baca)
  • Streptomycin (aph6id)
  • Aminoglycoside (emre)
  • Deoxycholate (mdtg)
  • Fosfomycin (mdtg)
  • Aminoglycoside (acra)
  • Glycylcycline (acra)
  • Macrolide (acra)
  • Beta lactam (acra)
  • Acriflavin (acra)
  • Cephalosproin (bl1_ec)
  • T chloride (mdto)
  • Acriflavine (mdto)
  • Puromycin (mdto)
  • Sulfonamide (sul2)
  • T chloride (mdtp)
  • Acriflavine (mdtp)
  • Puromycin (mdtp)
  • Doxorubicin (mdte)
  • Erythromycin (mdte)
  • Trimethoprim (dfra1)
  • Macrolide (maca)
  • Tetracycline (teta)
  • Kasugamycin (ksga)
  • Macrolide (macb)
  • Tetracycline (tetb)
  • Fluoroquinolone (qnrs)
  • Monobactam (bl2be_ctxm)
  • Cephalosporin ii (bl2be_ctxm)
  • Cephalosporin iii (bl2be_ctxm)
  • Penicillin (bl2be_ctxm)
  • Cephalosporin i (bl2be_ctxm)
  • Ceftazidime (bl2be_ctxm)
  • Aminoglycoside (tolc)
  • Glycylcycline (tolc)
  • Macrolide (tolc)
  • Beta lactam (tolc)
  • Acriflavin (tolc)
  • Enoxacin (mdtk)
  • Norfloxacin (mdtk)
  • Cephalosporin (bl2b_tem)
  • Penicillin (bl2b_tem)
  • Cloxacillin (bl2d_oxa1)
  • Penicillin (bl2d_oxa1)
  • Cephalosproin (bl3_imp)
  • Cephamycin (bl3_imp)
  • Penicillin (bl3_imp)
  • Carbapenem (bl3_imp)
  • Cephalosporin ii (bl2b_tem1)
  • Penicillin (bl2b_tem1)
  • Cephalosporin i (bl2b_tem1)
  • Chloramphenicol (cata3)
  • Chloramphenicol (catb3)
  • Streptomycin (aph33ib)
  • Chloramphenicol (mdtl)
  • BIOFILM FORMERS   COGEM PATHOGENICITY   

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