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Haemophilus

RANK: Genus

TAXONOMY: cellular organisms -> Bacteria -> Proteobacteria -> Gammaproteobacteria -> Pasteurellales -> Pasteurellaceae -> Haemophilus

OVERVIEW:

Minute to medium-sized coccobacilli or rods, generally less than 1 µm in width and variable in length, sometimes forming threads or filaments and showing marked pleomorphism. Gram negative. Nonmotile. Aerobic or facultatively anaerobic. Require preformed growth factors present in blood, particularly X factor (protoporphyrin IX or protoheme) and/or V factor (nicotinamide adenine dinucleotide [NAD] or NAD phosphate [NADP]). Even after specific growth factors have been provided, growth is best on complex media. Optimum temperature, 35–37°C. Nitrates are reduced to or beyond nitrites. Oxidase and catalase reactions vary among strains. Chemoorganotrophic. All species can attack carbohydrates fermentatively, yielding acetic, lactic, and succinic acids as end products in glucose broth. Occur as obligate parasites on the mucous membranes of humans and a variety of animal species. Several 16S rRNA sequence signatures for the family Pasteurellaceae have been demonstrated, but none of these is specific for the genus Haemophilus as presently defined (Dewhirst et al., 1992).The mol% G + C of the DNA is: 37–44.Type species: Haemophilus influenzae

This genus contains microbial species that can reside in the human gastrointestinal tract. [PMC 4262072]



Microbial Abundance Data: Haemophilus
(Percent of total population with standard deviation [PMID: 22698087])
Group 1
Group 2
Group 3
Group 4
Group 1 Avg
Buccal
Mucosa
Keratinized
Gingiva
Hard
Palate
Group 2 Avg
Throat
Throat
Tonsils
Saliva
Group 3 Avg
Supragingival
Plaque
Subgingival
Plaque
Stool
4.108 %
(3.993)
3.506 %
(4.104)
6.585 %
(5.831)
2.234 %
(2.043)
2.245 %
(3.791)
2.325 %
(7.193)
1.917 %
(2.266)
2.425 %
(2.915)
2.313 %
(2.792)
0.716 %
(1.151)
0.852 %
(1.409)
0.581 %
(0.893)
0.008 %
(0.031)
TAGS
Keystone
Core species
Type species
Pathogen
Dysbiosis associated
Flora/ commensal
Gut associated
Probiotic
Leanness
Obesity
Skin microbiome
Fecal distribution
Oral microbiome
Vaginal microbiome
Butyrate producer
Catalase producer
Histamine producer
Food fermenter
Amylolytic
Propionate producer
Nitrifying
Biofilm producer
DESCENDANTS
INTERACTIONS
KEGG PATHWAYS
  • 2-Oxocarboxylic acid metabolism
  • ABC transporters
  • Alanine, aspartate and glutamate metabolism
  • Amino sugar and nucleotide sugar metabolism
  • Aminoacyl-tRNA biosynthesis
  • Aminobenzoate degradation
  • Arginine and proline metabolism
  • Arginine biosynthesis
  • Ascorbate and aldarate metabolism
  • Bacterial chemotaxis
  • Bacterial secretion system
  • Base excision repair
  • Biosynthesis of amino acids
  • Biosynthesis of antibiotics
  • Biosynthesis of secondary metabolites
  • Biosynthesis of unsaturated fatty acids
  • Biotin metabolism
  • Butanoate metabolism
  • C5-Branched dibasic acid metabolism
  • Carbapenem biosynthesis
  • Carbon metabolism
  • Cationic antimicrobial peptide (CAMP) resistance
  • Chloroalkane and chloroalkene degradation
  • Citrate cycle (TCA cycle)
  • Cyanoamino acid metabolism
  • Cysteine and methionine metabolism
  • D-Alanine metabolism
  • D-Glutamine and D-glutamate metabolism
  • DNA replication
  • Degradation of aromatic compounds
  • Fatty acid biosynthesis
  • Fatty acid degradation
  • Fatty acid metabolism
  • Folate biosynthesis
  • Fructose and mannose metabolism
  • Galactose metabolism
  • Glutathione metabolism
  • Glycerolipid metabolism
  • Glycerophospholipid metabolism
  • Glycine, serine and threonine metabolism
  • Glycolysis / Gluconeogenesis
  • Glyoxylate and dicarboxylate metabolism
  • Histidine metabolism
  • Homologous recombination
  • Inositol phosphate metabolism
  • Insulin resistance
  • Lipoic acid metabolism
  • Lipopolysaccharide biosynthesis
  • Lysine biosynthesis
  • Lysine degradation
  • Metabolic pathways
  • Methane metabolism
  • Microbial metabolism in diverse environments
  • Mismatch repair
  • Monobactam biosynthesis
  • Naphthalene degradation
  • Nicotinate and nicotinamide metabolism
  • Nitrogen metabolism
  • Novobiocin biosynthesis
  • Nucleotide excision repair
  • One carbon pool by folate
  • Oxidative phosphorylation
  • Pantothenate and CoA biosynthesis
  • Pentose and glucuronate interconversions
  • Pentose phosphate pathway
  • Peptidoglycan biosynthesis
  • Phenylalanine metabolism
  • Phenylalanine, tyrosine and tryptophan biosynthesis
  • Phosphotransferase system (PTS)
  • Porphyrin and chlorophyll metabolism
  • Propanoate metabolism
  • Protein export
  • Purine metabolism
  • Pyrimidine metabolism
  • Pyruvate metabolism
  • RNA degradation
  • RNA polymerase
  • Riboflavin metabolism
  • Ribosome
  • Selenocompound metabolism
  • Starch and sucrose metabolism
  • Streptomycin biosynthesis
  • Sulfur metabolism
  • Sulfur relay system
  • Taurine and hypotaurine metabolism
  • Terpenoid backbone biosynthesis
  • Thiamine metabolism
  • Tryptophan metabolism
  • Two-component system
  • Tyrosine metabolism
  • Ubiquinone and other terpenoid-quinone biosynthesis
  • Valine, leucine and isoleucine biosynthesis
  • Valine, leucine and isoleucine degradation
  • Vancomycin resistance
  • Vitamin B6 metabolism
  • beta-Lactam resistance

  • CLUSTERS WITH
    METABOLOMICS       
    NUTRIENTS/ SUBSTRATES
  • D-Glucose

  • ENDPRODUCTS
  • Lactic acid
  • Acetic acid
  • Succinic acid
  • ANTIBIOTIC RESISTANCE   BIOFILM FORMERS   COGEM PATHOGENICITY   

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