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Megasphaera

RANK: Genus

TAXONOMY: Bacteria -> Terrabacteria group -> Firmicutes -> Negativicutes -> Selenomonadales -> Veillonellaceae -> Megasphaera

OVERVIEW:

'Megasphaera' is a genus of Firmicutes bacteria classified within the class Negativicutes.Anaerobic. Gram-stain-negative cocci, 0.4–2.0 µm or more in diameter. Nonmotile. Endospores not formed. Glucose, fructose, and lactate may or may not be fermented. Gas may or may not be produced. Gelatin or milk is not hydrolysed and nitrate is not reduced. Pyruvate but not succinate is utilized. Common metabolic end products of all five species described are acetic, propionic, butyric, and valeric acid. Found in the rumen of cattle and sheep, in the feces and intestine of man, in human clinical samples, and in spoiled bottled beer.DNA G+C content (mol%): 42.4–46.4 (Tm), 53.6 (Bd).Type species: Megasphaera elsdenii

This genus contains microbial species that can reside in the human gastrointestinal tract. [PMC 4262072]



Microbial Abundance Data: Megasphaera
(Percent of total population with standard deviation [PMID: 22698087])
Group 1
Group 2
Group 3
Group 4
Group 1 Avg
Buccal
Mucosa
Keratinized
Gingiva
Hard
Palate
Group 2 Avg
Throat
Throat
Tonsils
Saliva
Group 3 Avg
Supragingival
Plaque
Subgingival
Plaque
Stool
0.129 %
(0.236)
0.061 %
(0.130)
0.011 %
(0.062)
0.314 %
(0.515)
0.602 %
(0.767)
0.735 %
(0.944)
0.426 %
(0.599)
0.438 %
(0.578)
0.810 %
(0.947)
0.030 %
(0.193)
0.012 %
(0.078)
0.048 %
(0.308)
0.040 %
(0.245)
TAGS
Keystone
Core species
Type species
Pathogen
Dysbiosis associated
Flora/ commensal
Gut associated
Probiotic
Leanness
Obesity
Skin microbiome
Fecal distribution
Oral microbiome
Vaginal microbiome
Butyrate producer
Catalase producer
Histamine producer
Food fermenter
Amylolytic
Propionate producer
Nitrifying
Biofilm producer
DESCENDANTS
INTERACTIONS
KEGG PATHWAYS
  • 2-Oxocarboxylic acid metabolism
  • ABC transporters
  • Acarbose and validamycin biosynthesis
  • Alanine, aspartate and glutamate metabolism
  • Amino sugar and nucleotide sugar metabolism
  • Aminoacyl-tRNA biosynthesis
  • Aminobenzoate degradation
  • Arachidonic acid metabolism
  • Arginine and proline metabolism
  • Arginine biosynthesis
  • Bacterial secretion system
  • Base excision repair
  • Benzoate degradation
  • Biosynthesis of amino acids
  • Biosynthesis of antibiotics
  • Biosynthesis of secondary metabolites
  • Biosynthesis of unsaturated fatty acids
  • Biotin metabolism
  • Butanoate metabolism
  • C5-Branched dibasic acid metabolism
  • Carbapenem biosynthesis
  • Carbon metabolism
  • Cationic antimicrobial peptide (CAMP) resistance
  • Chloroalkane and chloroalkene degradation
  • Citrate cycle (TCA cycle)
  • Cyanoamino acid metabolism
  • Cysteine and methionine metabolism
  • D-Alanine metabolism
  • D-Glutamine and D-glutamate metabolism
  • DNA replication
  • Degradation of aromatic compounds
  • Fatty acid biosynthesis
  • Fatty acid degradation
  • Fatty acid metabolism
  • Folate biosynthesis
  • Fructose and mannose metabolism
  • Galactose metabolism
  • Glutathione metabolism
  • Glycerolipid metabolism
  • Glycerophospholipid metabolism
  • Glycine, serine and threonine metabolism
  • Glycolysis / Gluconeogenesis
  • Glyoxylate and dicarboxylate metabolism
  • Histidine metabolism
  • Homologous recombination
  • Lipopolysaccharide biosynthesis
  • Lysine biosynthesis
  • Lysine degradation
  • Metabolic pathways
  • Methane metabolism
  • Microbial metabolism in diverse environments
  • Mismatch repair
  • Monobactam biosynthesis
  • Naphthalene degradation
  • Nicotinate and nicotinamide metabolism
  • Nitrogen metabolism
  • Novobiocin biosynthesis
  • Nucleotide excision repair
  • One carbon pool by folate
  • Oxidative phosphorylation
  • Pantothenate and CoA biosynthesis
  • Pentose and glucuronate interconversions
  • Pentose phosphate pathway
  • Peptidoglycan biosynthesis
  • Phenylalanine metabolism
  • Phenylalanine, tyrosine and tryptophan biosynthesis
  • Phosphonate and phosphinate metabolism
  • Phosphotransferase system (PTS)
  • Polyketide sugar unit biosynthesis
  • Porphyrin and chlorophyll metabolism
  • Propanoate metabolism
  • Protein export
  • Purine metabolism
  • Pyrimidine metabolism
  • Pyruvate metabolism
  • Quorum sensing00253
  • RNA degradation
  • RNA polymerase
  • Riboflavin metabolism
  • Ribosome
  • Selenocompound metabolism
  • Starch and sucrose metabolism
  • Streptomycin biosynthesis
  • Styrene degradation
  • Sulfur metabolism
  • Sulfur relay system
  • Taurine and hypotaurine metabolism
  • Terpenoid backbone biosynthesis
  • Thiamine metabolism
  • Tryptophan metabolism
  • Two-component system
  • Tyrosine metabolism
  • Ubiquinone and other terpenoid-quinone biosynthesis
  • Valine, leucine and isoleucine biosynthesis
  • Valine, leucine and isoleucine degradation
  • Vancomycin resistance
  • Vitamin B6 metabolism
  • beta-Alanine metabolism
  • beta-Lactam resistance

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