Datapunk Opus23 | Ralstonia

Ralstonia

RANK: Genus

TAXONOMY: cellular organisms -> Bacteria -> Proteobacteria -> Betaproteobacteria -> Burkholderiales -> Burkholderiaceae -> Ralstonia

OVERVIEW:

Gram-negative asporogenous rods. Motile or nonmotile; motile species have either a single polar flagellum or peritrichous flagella. Aerobic, having a strictly respiratory type of metabolism with oxygen as the terminal electron acceptor. Able to grow on ordinary peptone media. One species, R. eutropha, is a facultatively chemolithoautotrophic organism (a knallgas bacterium) and can oxidize H2 as an electron donor. Furthermore, under anaerobic conditions, R. eutropha is able to utilize nitrate as the terminal electron acceptor. Colony color is beige in most species. Strains of R. eutropha are regarded as having outstanding biotechnological potential. Oxidase and catalase positive. Lysine and ornithine decarboxylase negative. Ubiquinone Q-8 is the major respiratory quinone. None of the 26 carbohydrates tested are oxidized by the type strains of R. campinensis and R. taiwanensis. Among 95 other organic compounds, 10—mainly salts of organic acids—were assimilated and 39 other compounds were not assimilated by all of the 11 type strains. Cellular lipids of this genus contain two kinds of phosphatidylethanolamine, PE-1 and PE-2. The latter possesses 2-hydroxy fatty acid at sn-2 position of the glycerol moiety. Major components of cellular fatty acids are C16:0, a mixture of C18:1 ω9t and C18:1 ω7c, and C14:0 3OH. At present the genus is composed of 11 validated species. The sequence similarity of 11 type strains to that of Ralstonia pickettii—the type species—ranges from 95.0% to 98.1%. The genus contains plant pathogens, human pathogens, knallgas bacteria, and metal-resistant bacteria.

The mol% G + C of the DNA is: 64.0–68.0.

This genus contains microbial species that can reside in the human gastrointestinal tract. [PMC 4262072]

Microbial Abundance Data: Ralstonia (Percent of total population with standard deviation [PMID: 22698087])
Group 1				Group 2					Group 3			Group 4
Group 1 Avg	Buccal Mucosa	Keratinized Gingiva	Hard Palate	Group 2 Avg	Throat	Throat	Tonsils	Saliva	Group 3 Avg	Supragingival Plaque	Subgingival Plaque	Stool
0.011 % (0.058)	0.014 % (0.079)	0.005 % (0.020)	0.015 % (0.073)	0.063 % (0.502)	0.047 % (0.196)	0.004 % (0.031)	0.002 % (0.018)	0.198 % (1.763)	0.005 % (0.040)	0.001 % (0.004)	0.010 % (0.076)	0.002 % (0.022)

TAGS

Keystone	Core species	Type species	Pathogen	Dysbiosis associated	Flora/ commensal	Gut associated	Probiotic
Leanness	Obesity	Skin microbiome	Fecal distribution	Oral microbiome	Vaginal microbiome	Butyrate producer	Catalase producer
Histamine producer	Food fermenter	Amylolytic	Propionate producer	Nitrifying

DESCENDANTS Ralstonia detusculanense Ralstonia insidiosa Ralstonia mannitolilytica Ralstonia pickettii Ralstonia pseudosolanacearum Ralstonia solanacearum Ralstonia sp. Ralstonia sp. CCUG 46389 Ralstonia sp. S2.MAC.005 Ralstonia syzygii environmental samples unclassified Ralstonia	INTERACTIONS	KEGG PATHWAYS 2-Oxocarboxylic acid metabolism ABC transporters Alanine, aspartate and glutamate metabolism Amino sugar and nucleotide sugar metabolism Aminoacyl-tRNA biosynthesis Aminobenzoate degradation Arachidonic acid metabolism Arginine and proline metabolism Arginine biosynthesis Ascorbate and aldarate metabolism Bacterial chemotaxis Bacterial secretion system Base excision repair Benzoate degradation Biosynthesis of amino acids Biosynthesis of antibiotics Biosynthesis of secondary metabolites Biosynthesis of unsaturated fatty acids Biotin metabolism Butanoate metabolism C5-Branched dibasic acid metabolism Caprolactam degradation Carbapenem biosynthesis Carbon metabolism Carotenoid biosynthesis Cationic antimicrobial peptide (CAMP) resistance Chloroalkane and chloroalkene degradation Chlorocyclohexane and chlorobenzene degradation Citrate cycle (TCA cycle) Cyanoamino acid metabolism Cysteine and methionine metabolism D-Alanine metabolism D-Arginine and D-ornithine metabolism D-Glutamine and D-glutamate metabolism DNA replication Degradation of aromatic compounds Dioxin degradation Fatty acid biosynthesis Fatty acid degradation Fatty acid metabolism Flagellar assembly Fluorobenzoate degradation Folate biosynthesis Fructose and mannose metabolism Furfural degradation Galactose metabolism Geraniol degradation Glutathione metabolism Glycerolipid metabolism Glycerophospholipid metabolism Glycine, serine and threonine metabolism Glycolysis / Gluconeogenesis Glyoxylate and dicarboxylate metabolism Histidine metabolism Homologous recombination Inositol phosphate metabolism Insulin resistance Limonene and pinene degradation Lipoic acid metabolism Lipopolysaccharide biosynthesis Lysine biosynthesis Lysine degradation Metabolic pathways Methane metabolism Microbial metabolism in diverse environments Mismatch repair Monobactam biosynthesis Naphthalene degradation Nicotinate and nicotinamide metabolism Nitrogen metabolism Nitrotoluene degradation Non-homologous end-joining Novobiocin biosynthesis Nucleotide excision repair One carbon pool by folate Oxidative phosphorylation Pantothenate and CoA biosynthesis Pentose and glucuronate interconversions Pentose phosphate pathway Peptidoglycan biosynthesis Phenylalanine metabolism Phenylalanine, tyrosine and tryptophan biosynthesis Phosphonate and phosphinate metabolism Phosphotransferase system (PTS) Polyketide sugar unit biosynthesis Porphyrin and chlorophyll metabolism Propanoate metabolism Protein export Purine metabolism Pyrimidine metabolism Pyruvate metabolism RNA degradation RNA polymerase Riboflavin metabolism Ribosome Selenocompound metabolism Starch and sucrose metabolism Streptomycin biosynthesis Styrene degradation Sulfur metabolism Sulfur relay system Synthesis and degradation of ketone bodies Taurine and hypotaurine metabolism Terpenoid backbone biosynthesis Thiamine metabolism Toluene degradation Tryptophan metabolism Two-component system Tyrosine metabolism Ubiquinone and other terpenoid-quinone biosynthesis Valine, leucine and isoleucine biosynthesis Valine, leucine and isoleucine degradation Vancomycin resistance Vitamin B6 metabolism Xylene degradation alpha-Linolenic acid metabolism beta-Alanine metabolism beta-Lactam resistance CLUSTERS WITH	METABOLOMICS NUTRIENTS/ SUBSTRATES H2 ENDPRODUCTS Polyhydroxyalkanoic acids INHIBITED BY Vitamin D ENHANCED BY BIOTRANSFORMS BIOTRANFORM
ANTIBIOTIC RESISTANCE Glycylcycline (mexc) Fluoroquinolone (mexc) Roxithromycin (mexc) Erythromycin (mexc)	BIOFILM FORMERS Ralstonia sp 5 2 56FAA Ralstonia sp AU12 08 Ralstonia solanacearum Ralstonia pickettii Ralstonia sp 5 7 47FAA	COGEM PATHOGENICITY Ralstonia sp 5 2 56FAA (2) Ralstonia sp AU12 08 (2) Ralstonia solanacearum (2) Ralstonia pickettii (2) Ralstonia sp 5 7 47FAA (2)

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