 | ||||||
Enterococcus gallinarumRANK: SpeciesTAXONOMY: Terrabacteria group -> Firmicutes -> Bacilli -> Lactobacillales -> Enterococcaceae -> Enterococcus -> Enterococcus gallinarum OVERVIEW: Identified as constituent of vaginal microbiome. [PMID:23282177] This species has been identified as a resident in the human gastrointestinal tract based on the phylogenetic framework of its small subunit ribosomal RNA gene sequences.[PMC 4262072] Translocation of the gut pathobiont Enterococcus gallinarum to the liver and other systemic tissues triggers autoimmune responses in a genetic background predisposing to autoimmunity. Antibiotic treatment prevented mortality in this model, suppressed growth of E. gallinarum in tissues, and eliminated pathogenic autoantibodies and T cells. [PMID:29590047]
|