Enterococcus faecium

RANK: Species

TAXONOMY: Terrabacteria group -> Firmicutes -> Bacilli -> Lactobacillales -> Enterococcaceae -> Enterococcus -> Enterococcus faecium

OVERVIEW:

Enterococcus faecium is a Gram-positive, alpha-hemolytic or nonhemolytic bacterium in the genus Enterococcus. It can be commensal (innocuous, coexisting organism) in the human intestine, but it may also be pathogenic, causing diseases such as neonatal meningitis or endocarditis. Vancomycin-resistant E. faecium is often referred to as VRE.[Some strains of E. faecium are used as probiotics in both animals, and humans. A probiotic that contains Enterococcus faecium (SF68 strain) has been proposed elsewhere to be clinically effective in the prevention of antibiotic-associated diarrhea and in the treatment of diarrhea in children . However, in another study, no antidiarrheal property of E. faecium (SF68) was found. E. faecium is a human pathogen that causes nosocomial bacteremia, surgical wound infection, endocarditis, and urinary tract infections.

This species has been identified as a resident in the human gastrointestinal tract based on the phylogenetic framework of its small subunit ribosomal RNA gene sequences.[PMC 4262072]

2

COGEM

COGEM released a comprehensive database of pathogenicity assessment of around 2575 bacterial species in 2011. The database ranks the pathogenicity of species on a scale of 1 to 4. Enterococcus faecium ranks 2 on this scale: Species that can cause diseases in humans or animals, which are unlikely to spread in the human population and for which an adequate prophylaxis or therapy exists

TAGS >

Keystone	Core species	Type species	Pathogen	Dysbiosis associated	Flora/ commensal	Gut associated	Probiotic
Leanness	Obesity	Skin microbiome	Fecal distribution	Oral microbiome	Vaginal microbiome	Butyrate producer	Catalase producer
Histamine producer	Food fermenter	Amylolytic	Propionate producer	Nitrifying	Biofilm producer

INTERACTIONS INHIBITS Peptoclostridium INHIBITED BY Lactobacillus Barnesiella Coprobacillus	KEGG PATHWAYS CLUSTERS WITH	METABOLOMICS NUTRIENTS/ SUBSTRATES Lactate [parent] D-Glucose [parent] Mucins [parent] Malate [parent] Gluten [parent] ENDPRODUCTS Tyramine 5-hydroxytryptamine (5-HT, Serotonin) [parent] Lactic acid [parent] INHIBITED BY Polymannuronic acid [parent] Glyphosphate [parent] Propolis [parent] Trametes versicolor [parent] Glycyrrhizic acid [parent] Resistant starch (type IV) [parent] Hyperiform [parent] Triphala [parent] ENHANCED BY Sesame cake/meal [parent] Chemotherapy [parent] Red wine [parent] Navy bean (Cooked) [parent] Esculin [parent] High fat diet [parent] Bile [parent] BIOTRANSFORMS Daidzein BIOTRANFORM Equol sulphate
ANTIBIOTIC RESISTANCE See Parent Genus (Enterococcus)	BIOFILM FORMERS See Parent Genus (Enterococcus)	COGEM PATHOGENICITY See Parent Genus (Enterococcus)