Corynebacterium urealyticum

RANK: Species

TAXONOMY: Terrabacteria group -> Actinobacteria -> Actinobacteria -> Corynebacteriales -> Corynebacteriaceae -> Corynebacterium -> Corynebacterium urealyticum


Was previously provisional taxon C28 in RefSeq Extended V1.1 Identified as a constituent of the oral microbiome by Human Oral Microbiome Database. Corynebacterium urealyticum is a bacterial species of the Corynebacterium genus. It is not commonly found in healthy people. It is, however, an important isolate when found in conjunction with a urinary tract infection. In contrast to acid-producing bacteria like Escherichia coli, C. urealyticum, as the name implies, secretes urease enzyme which is strong enough to make urine alkaline. This can lead to the formation of struvite calculi or renal stones. Risk factors associated with this bacterium include, immunosuppression, underlying genitourinay disorders, as well as antibiotic therapy. There are other urease-producing cornybacteria that are associated with urinary tract infections, but C. urealyticum is the most common.

Oral microbiome
Substrates/ Growth Factors
  • Urea

  • Metabolic Endproducts
  • Ammonia

  • Growth Inhibited by
  • Aloe vera [parent]

  • Growth Enhanced By
  • Proton-pump inhibitors (PPI) [parent]