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Phascolarctobacterium

RANK: Genus

TAXONOMY: Bacteria -> Terrabacteria group -> Firmicutes -> Negativicutes -> Selenomonadales -> Acidaminococcaceae -> Phascolarctobacterium

OVERVIEW:

Genus in family Succiniclasticum. Pleomorphic rods, 0.5 × 2.0 µm to 0.5 × 5–20 µm. Pleomorphism is medium dependent; in the presence of succinate small rods are transformed into elongated and fragmented rods with multiple branches. Gram-stain-negative, nonmotile, nonspore-forming chemo-organotroph. Propionic acid is the main end product of succinate fermentation. Growth inhibited by fumarate. Growth of satellite colonies around colonies of succinate-producing Escherichia coli cells. Obligately anaerobic. Growth most rapid at 30–37°C. Phylogenetically a member of the family Veillonellaceae, phylum Firmicutes. So far Succiniclasticum ruminis is the closest phylogenetic neighbor.

This genus contains microbial species that can reside in the human gastrointestinal tract. [PMC 4262072]

Microbial Abundance Data: Phascolarctobacterium (Percent of total population with standard deviation [PMID: 22698087])
Group 1				Group 2					Group 3			Group 4
Group 1 Avg	Buccal Mucosa	Keratinized Gingiva	Hard Palate	Group 2 Avg	Throat	Throat	Tonsils	Saliva	Group 3 Avg	Supragingival Plaque	Subgingival Plaque	Stool
0.001 % (0.007)	0.001 % (0.003)	0.001 % (0.006)	0.002 % (0.012)	0.002 % (0.010)	0.002 % (0.007)	0.001 % (0.006)	0.001 % (0.009)	0.003 % (0.017)	0.001 % (0.012)	0.000 % (0.001)	0.002 % (0.023)	0.766 % (1.398)

TAGS

Keystone	Core species	Type species	Pathogen	Dysbiosis associated	Flora/ commensal	Gut associated	Probiotic
Leanness	Obesity	Skin microbiome	Fecal distribution	Oral microbiome	Vaginal microbiome	Butyrate producer	Catalase producer
Histamine producer	Food fermenter	Amylolytic	Propionate producer	Nitrifying

DESCENDANTS Phascolarctobacterium faecium Phascolarctobacterium sp. 377 Phascolarctobacterium sp. canine oral taxon 149 Phascolarctobacterium succinatutens environmental samples	INTERACTIONS ENHANCES Bacteroidales Bacteroides Odoribacter Peptococcaceae INHIBITS Bifidobacterium Coriobacteriales Adlercreutzia Collinsella Porphyromonas Prevotella Clostridium Clostridiales incertae sedis Clostridiales Family XIII. Incertae Sedis Blautia Coprococcus Dorea Lachnospiraceae Ruminococcaceae Ruminococcus Dialister Campylobacteraceae Erysipelotrichaceae	KEGG PATHWAYS CLUSTERS WITH	METABOLOMICS NUTRIENTS/ SUBSTRATES Succinate ENDPRODUCTS Propionic acid INHIBITED BY Fumarate Sodium chloride Resistant starch (type II) ENHANCED BY Berberine BIOTRANSFORMS BIOTRANFORM
ANTIBIOTIC RESISTANCE	BIOFILM FORMERS	COGEM PATHOGENICITY