Datapunk Opus23 | Acidaminococcus

Acidaminococcus

RANK: Genus

TAXONOMY: Bacteria -> Terrabacteria group -> Firmicutes -> Negativicutes -> Selenomonadales -> Acidaminococcaceae -> Acidaminococcus

OVERVIEW:

'Acidaminococcus' is a genus in the phylum Firmicutes (Bacteria), whose members are anaerobic diplococci that can use amino acids as the sole energy source for growth. Like other members of the class Negativicutes, they are gram-negative, despite being Firmicutes, which are normally gram-positive.Cells coccoid, 0.6–1.0 µm in diameter, often occurring as oval or kidney-shaped diplococci. Nonspore-forming. Gram-stain-negative. Nonmotile; flagella are not present. The cellwall contains meso-diaminopimelic acid; whole cells contain galactose, glucose, and ribose. Menaquinones and ubiquinones are absent. Anaerobic; no growth on the surface of agar media incubated in the air. Optimal growth at 30–37°C and pH 7.0. Oxidase and catalase-negative. Chemo-organotrophic: d- and l-Glutamate, trans-aconitate, and citrate are the known energy sources. Other amino acids, pyruvate, lactate, fumarate, malate, and succinate are not used as energy sources. Approximately 40% of the strains catabolize glucose, from which little acid is produced. On complex media, ammonia, CO2, acetate, butyrate, and hydrogen are produced, but propionate and valerate have not been detected. Glutamate is fermented to about 1.0 CO2, 1.0 ammonia, 1.2 acetate, 0.4 butyrate, and up to 10 kPa H2; citrate and trans-aconitate are fermented to about 2.0 CO2, 1.8 acetate, 0.1 butyrate, and 90 kPa H2. Nutritional requirements are complex. Isolated from the intestinal tract of the pig and humans. Has also been isolated from cattle rumen, but not usually a predominant ruminal bacterium.DNA G+C content (mol%): 54.7–57.4.Type species: Acidaminococcus fermentans

This genus contains microbial species that can reside in the human gastrointestinal tract. [PMC 4262072]

Microbial Abundance Data: Acidaminococcus (Percent of total population with standard deviation [PMID: 22698087])
Group 1				Group 2					Group 3			Group 4
Group 1 Avg	Buccal Mucosa	Keratinized Gingiva	Hard Palate	Group 2 Avg	Throat	Throat	Tonsils	Saliva	Group 3 Avg	Supragingival Plaque	Subgingival Plaque	Stool
0.000 % (0.002)	0.000 % (0.000)	0.000 % (0.000)	0.000 % (0.005)	0.000 % (0.000)	0.000 % (0.000)	0.000 % (0.001)	0.000 % (0.000)	0.000 % (0.000)	0.000 % (0.000)	0.000 % (0.000)	0.000 % (0.000)	0.068 % (0.264)

TAGS

Keystone	Core species	Type species	Pathogen	Dysbiosis associated	Flora/ commensal	Gut associated	Probiotic
Leanness	Obesity	Skin microbiome	Fecal distribution	Oral microbiome	Vaginal microbiome	Butyrate producer	Catalase producer
Histamine producer	Food fermenter	Amylolytic	Propionate producer	Nitrifying

DESCENDANTS Acidaminococcus fermentans Acidaminococcus intestini Acidaminococcus sp. BV3L6 Acidaminococcus sp. D21 Acidaminococcus sp. HPA0509 environmental samples	INTERACTIONS ENHANCES Bacteroidales Bacteroides Odoribacter Peptococcaceae INHIBITS Bifidobacterium Coriobacteriales Adlercreutzia Collinsella Porphyromonas Prevotella Clostridium Clostridiales incertae sedis Clostridiales Family XIII. Incertae Sedis Blautia Coprococcus Dorea Lachnospiraceae Ruminococcaceae Ruminococcus Dialister Campylobacteraceae Erysipelotrichaceae	KEGG PATHWAYS 2-Oxocarboxylic acid metabolism ABC transporters Acarbose and validamycin biosynthesis Alanine, aspartate and glutamate metabolism Amino sugar and nucleotide sugar metabolism Aminoacyl-tRNA biosynthesis Aminobenzoate degradation Arginine and proline metabolism Arginine biosynthesis Ascorbate and aldarate metabolism Bacterial secretion system Base excision repair Benzoate degradation Biosynthesis of amino acids Biosynthesis of antibiotics Biosynthesis of secondary metabolites Biosynthesis of unsaturated fatty acids Biotin metabolism Butanoate metabolism C5-Branched dibasic acid metabolism Carbapenem biosynthesis Carbon metabolism Cationic antimicrobial peptide (CAMP) resistance Chloroalkane and chloroalkene degradation Citrate cycle (TCA cycle) Cyanoamino acid metabolism Cysteine and methionine metabolism D-Alanine metabolism D-Glutamine and D-glutamate metabolism DNA replication Degradation of aromatic compounds Fatty acid biosynthesis Fatty acid degradation Fatty acid metabolism Folate biosynthesis Fructose and mannose metabolism Galactose metabolism Glutathione metabolism Glycerolipid metabolism Glycerophospholipid metabolism Glycine, serine and threonine metabolism Glycolysis / Gluconeogenesis Glyoxylate and dicarboxylate metabolism Histidine metabolism Homologous recombination Lipopolysaccharide biosynthesis Lysine biosynthesis Lysine degradation Metabolic pathways Methane metabolism Microbial metabolism in diverse environments Mismatch repair Monobactam biosynthesis Naphthalene degradation Nicotinate and nicotinamide metabolism Nitrogen metabolism Novobiocin biosynthesis Nucleotide excision repair One carbon pool by folate Oxidative phosphorylation Pantothenate and CoA biosynthesis Pentose and glucuronate interconversions Pentose phosphate pathway Peptidoglycan biosynthesis Phenylalanine metabolism Phenylalanine, tyrosine and tryptophan biosynthesis Phosphonate and phosphinate metabolism Phosphotransferase system (PTS) Polyketide sugar unit biosynthesis Porphyrin and chlorophyll metabolism Propanoate metabolism Protein export Purine metabolism Pyrimidine metabolism Pyruvate metabolism Quorum sensing00253 RNA degradation RNA polymerase Riboflavin metabolism Ribosome Selenocompound metabolism Starch and sucrose metabolism Streptomycin biosynthesis Styrene degradation Sulfur metabolism Sulfur relay system Taurine and hypotaurine metabolism Terpenoid backbone biosynthesis Thiamine metabolism Tryptophan metabolism Two-component system Tyrosine metabolism Valine, leucine and isoleucine biosynthesis Valine, leucine and isoleucine degradation Vancomycin resistance Vitamin B6 metabolism beta-Alanine metabolism beta-Lactam resistance CLUSTERS WITH	METABOLOMICS NUTRIENTS/ SUBSTRATES ENDPRODUCTS INHIBITED BY ENHANCED BY BIOTRANSFORMS BIOTRANFORM
ANTIBIOTIC RESISTANCE	BIOFILM FORMERS	COGEM PATHOGENICITY Acidaminococcus fermentans (2) Acidaminococcus intestini (2)

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