Roseburia hominis

RANK: Species

TAXONOMY: Terrabacteria group -> Firmicutes -> Clostridia -> Clostridiales -> Lachnospiraceae -> Roseburia -> Roseburia hominis

OVERVIEW:

Glucuronidase activity was induced by growth on d-glucuronic acid, or by addition of 4-nitrophenol-glucuronide, in Roseburia hominis A2-183, while beta-glucosidase activity was induced by 4-nitrophenol-glucopyranoside. Inducibility varied between strains. [PMID: 18537837]

This species has been identified as a resident in the human gastrointestinal tract based on the phylogenetic framework of its small subunit ribosomal RNA gene sequences.[PMC 4262072]

1

COGEM

COGEM released a comprehensive database of pathogenicity assessment of around 2575 bacterial species in 2011. The database ranks the pathogenicity of species on a scale of 1 to 4. Roseburia hominis ranks 1 on this scale: The species or strain does not belong to a recognized group of disease-invoking agents in humans or animals and/or has an extended history of safe usage under conditions without any physical restrictions

TAGS

Keystone	Core species	Type species	Pathogen	Dysbiosis associated	Flora/ commensal	Gut associated	Probiotic
Leanness	Obesity	Skin microbiome	Fecal distribution	Oral microbiome	Vaginal microbiome	Butyrate producer	Catalase producer
Histamine producer	Food fermenter	Amylolytic	Propionate producer	Nitrifying	Biofilm producer

INTERACTIONS ENHANCES Bacteroidales Bacteroides Odoribacter Peptococcaceae INHIBITS Bifidobacterium Coriobacteriales Adlercreutzia Collinsella Porphyromonas Prevotella Clostridium Clostridiales incertae sedis Clostridiales Family XIII. Incertae Sedis Blautia Coprococcus Dorea Lachnospiraceae Ruminococcaceae Ruminococcus Dialister Campylobacteraceae Erysipelotrichaceae ENHANCED BY Bifidobacterium Faecalibacterium	KEGG PATHWAYS CLUSTERS WITH	METABOLOMICS NUTRIENTS/ SUBSTRATES Resistant starch (type II) [parent] N-Acetyl-D-glucosamine [parent] Acetate [parent] β-Glucan [parent] Resistant starch (type III) [parent] Arabinoxylans [parent] Raffinose [parent] Stachyose (soy oligosaccharide) [parent] Chitin [parent] ENDPRODUCTS Lactate [parent] Butyrate [parent] Butyrate INHIBITED BY High animal protein diet [parent] Low carbohydrate diet [parent] Ketogenic diet [parent] High meat diet [parent] Epinephrine [parent] Fructo-oligosaccharides [parent] ENHANCED BY Resistant starch (type II) [parent] Almonds/ almond skins [parent] Polymannuronic acid [parent] Vitamin D [parent] N-Acetyl-D-glucosamine [parent] β-Glucan Dopamine [parent] β-Glucan [parent] Walnuts [parent] Whole-grain barley Arabinoxylans [parent] Dietary fiber [parent] BIOTRANSFORMS BIOTRANFORM
ANTIBIOTIC RESISTANCE See Parent Genus (Roseburia)	BIOFILM FORMERS See Parent Genus (Roseburia)	COGEM PATHOGENICITY See Parent Genus (Roseburia)