Lactobacillus fermentum

RANK: Species

TAXONOMY: Terrabacteria group -> Firmicutes -> Bacilli -> Lactobacillales -> Lactobacillaceae -> Lactobacillus -> Lactobacillus fermentum

OVERVIEW:

This probiotic strain, which has been found in the probiotic foods sourdough and kimchi, produces superoxide dismutase and glutathione, both powerful antioxidants that help neutralize some of the toxic products made in the gut during digestion. L. fermentum has also been isolated as exhibiting activity against foodborne pathogens. Identified as a constituent of the oral microbiome by Human Oral Microbiome Database. Identified as constituent of vaginal microbiome. [PMID:23282177]

This species has been identified as a resident in the human gastrointestinal tract based on the phylogenetic framework of its small subunit ribosomal RNA gene sequences.[PMC 4262072]


Food fermenter
Gut associated
Oral microbiome
Vaginal microbiome
INTERACTIONS

Lactobacillus fermentum inhibits growth of
  • Clostridioides difficile
  • Enterococcus
    		•
    METABOLOMICS   
    Substrates/ Growth Factors
  • Ellagic acid [parent]
  • D-Glucose [parent]
  • CO2 [parent]
  • α-Glucan [parent]

    • Metabolic Endproducts
  • Urolithins [parent]
  • Lactate [parent]
  • Acetylcholine [parent]
  • γ-Amino butyric acid (GABA) [parent]
  • Vitamin B12 [parent]
  • Trimethylamine [parent]
  • Lactic acid [parent]

    • Growth Inhibited by
  • Stevia [parent]
  • Laminaria hyperborea (curvie) [parent]
  • Chemotherapy [parent]
  • Magnesium-deficient diet [parent]
  • Glyphosphate [parent]
  • High fat diet [parent]
  • Sucralose (Splenda) [parent]

    • Growth Enhanced By
  • Sesame cake/meal [parent]
  • Almonds/ almond skins [parent]
  • Navy bean (Cooked) [parent]
  • Magnesium [parent]
  • Daesiho-tang (DSHT) [parent]
  • Resveratrol [parent]
  • Proton-pump inhibitors (PPI) [parent]
  • Laminaria digitata (oarweed) [parent]
  • Melatonin [parent]

    • Biotransforms
  • Linoleic acid (LA) [parent]
  • Linolenic acid (CLnA) [parent]

    • Transform Product
  • 10‐Hydroxy‐cis‐12‐octadecenoate (HYA) [parent]
  • Trans-11 conjugate linoleic acid (CLA) [parent]
  • Cis-9 conjugate linoleic acid (CLA) [parent]
  • Cis-15 conjugate linolenic acids (CLnA) [parent]
  • Cis-9 conjugate linolenic acids (CLnA) [parent]
  • 10-Hydroxyoctadecanoate (HYB) [parent]
  • Trans-11 conjugate linolenic acids (CLnA) [parent]