Alistipes putredinis

RANK: Species

TAXONOMY: Bacteroidetes/Chlorobi group -> Bacteroidetes -> Bacteroidia -> Bacteroidales -> Rikenellaceae -> Alistipes -> Alistipes putredinis

OVERVIEW:

Alistipes putredinis (GenBank Accession Number for 16S rDNA gene: L16497) is a member of the Bacteroidetes division of the domain bacteria and has been isolated from human feces. It has been found in 16S rDNA sequence-based enumerations of the colonic microbiota of adult humans (Eckburg et. al. (2005), Ley et. al. (2006)). The sequenced strain was obtained from Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH (DSMZ) (DSM# 17216). This is from the Human Microbiome Initiative. A species isolated from feces, cases of acute appendicitis, and abdominal and rectal abscesses; also from foot rot of sheep and from farm soil. Its properties are divergent from most Bacteroides species. Three members of the Bacteroidetes, Bacteroides uniformis, Parabacteroides merdae, and Alistipes putredinis positively correlated with cecal acetate, propionate and butyrate levels. Whereas members of these species generate acetate and propionate, their ability to produce butyrate has not been reported. Their positive association with butyrate levels could be due to interspecies acetate cross-feeding with butyrate-producing taxa. [PMC 3829625] Alistipes is a bile tolerant organism. Synonym: Bacteroides putredinis

This species has been identified as a resident in the human gastrointestinal tract based on the phylogenetic framework of its small subunit ribosomal RNA gene sequences.[PMC 4262072]

2

COGEM

COGEM released a comprehensive database of pathogenicity assessment of around 2575 bacterial species in 2011. The database ranks the pathogenicity of species on a scale of 1 to 4. Alistipes putredinis ranks 2 on this scale: Species that can cause diseases in humans or animals, which are unlikely to spread in the human population and for which an adequate prophylaxis or therapy exists

Identified as a 'core species' of the human gut microbiome. [PMID: 23222524]

TAGS

Keystone	Core species	Type species	Pathogen	Dysbiosis associated	Flora/ commensal	Gut associated	Probiotic
Leanness	Obesity	Skin microbiome	Fecal distribution	Oral microbiome	Vaginal microbiome	Butyrate producer	Catalase producer
Histamine producer	Food fermenter	Amylolytic	Propionate producer	Nitrifying	Biofilm producer

INTERACTIONS ENHANCES Bacteroidales Bacteroides Odoribacter Peptococcaceae INHIBITS Bifidobacterium Coriobacteriales Adlercreutzia Collinsella Porphyromonas Prevotella Clostridium Clostridiales incertae sedis Clostridiales Family XIII. Incertae Sedis Blautia Coprococcus Dorea Lachnospiraceae Ruminococcaceae Ruminococcus Dialister Campylobacteraceae Erysipelotrichaceae INHIBITED BY Faecalibacterium	KEGG PATHWAYS CLUSTERS WITH	METABOLOMICS NUTRIENTS/ SUBSTRATES D-Glucose [parent] Thiamine [parent] L-Tryptophan [parent] ENDPRODUCTS Succinic acid [parent] Indole [parent] Acetic acid [parent] Propionate Acetate INHIBITED BY Plant-rich diet [parent] Tannin [parent] Gallate [parent] Cranberry bean flour [parent] ENHANCED BY High meat diet [parent] High fat diet [parent] High protein diet High fruit intake [parent] BIOTRANSFORMS BIOTRANFORM
ANTIBIOTIC RESISTANCE See Parent Genus (Alistipes)	BIOFILM FORMERS See Parent Genus (Alistipes)	COGEM PATHOGENICITY See Parent Genus (Alistipes)