Parabacteroides distasonis

RANK: Species

TAXONOMY: Bacteroidetes/Chlorobi group -> Bacteroidetes -> Bacteroidia -> Bacteroidales -> Porphyromonadaceae -> Parabacteroides -> Parabacteroides distasonis

OVERVIEW:

Parabacteroides distasonis (also known as Bacteroides distasonis) is a member of the normal distal human gut microbiota. The distal gut microbiota contain more bacterial cells than all of our body's other microbial communities combined. More than 90% of phylogenetic types belong to two divisions, the Bacteroidetes and the Firmicutes, with the remaining types distributed among eight other divisions. P. distasonis has the smallest genome among the sequenced human gut-associated Bacteroidetes, the smallest repertoire of genes involved in environmental sensing and gene regulation and the smallest number of genes associated with carbon source degradation. It lacks many accessory hemicellulases, pectinases and polysaccharidases that target non-plant carbohydrates. Synonyms : Ristella distasonis, Pseudobacterium distasonis, NCTC 11152, JCM 5825, DSM 20701, CIP 104284, CCUG 4941, Bacteroides fragilis subsp. distasoni, Bacteroides distasonis, ATCC 8503

This species has been identified as a resident in the human gastrointestinal tract based on the phylogenetic framework of its small subunit ribosomal RNA gene sequences.[PMC 4262072]

2

COGEM

COGEM released a comprehensive database of pathogenicity assessment of around 2575 bacterial species in 2011. The database ranks the pathogenicity of species on a scale of 1 to 4. Parabacteroides distasonis ranks 2 on this scale: Species that can cause diseases in humans or animals, which are unlikely to spread in the human population and for which an adequate prophylaxis or therapy exists

TAGS

Keystone	Core species	Type species	Pathogen	Dysbiosis associated	Flora/ commensal	Gut associated	Probiotic
Leanness	Obesity	Skin microbiome	Fecal distribution	Oral microbiome	Vaginal microbiome	Butyrate producer	Catalase producer
Histamine producer	Food fermenter	Amylolytic	Propionate producer	Nitrifying	Biofilm producer

INTERACTIONS ENHANCES Bacteroidales Bacteroides Odoribacter Peptococcaceae INHIBITS Bifidobacterium Coriobacteriales Adlercreutzia Collinsella Porphyromonas Prevotella Clostridium Clostridiales incertae sedis Clostridiales Family XIII. Incertae Sedis Blautia Coprococcus Dorea Lachnospiraceae Ruminococcaceae Ruminococcus Dialister Campylobacteraceae Erysipelotrichaceae	KEGG PATHWAYS CLUSTERS WITH	METABOLOMICS NUTRIENTS/ SUBSTRATES ENDPRODUCTS INHIBITED BY ENHANCED BY Ketogenic diet [parent] Epinephrine Proton-pump inhibitors (PPI) [parent] Dopamine Resistant starch (type IV) [parent] BIOTRANSFORMS Myricetin Lignans BIOTRANFORM Trimethylamine-N-oxide (TMAO) [parent] Trimethylamine [parent] Enterolignans
ANTIBIOTIC RESISTANCE See Parent Genus (Parabacteroides)	BIOFILM FORMERS See Parent Genus (Parabacteroides)	COGEM PATHOGENICITY See Parent Genus (Parabacteroides)