Lactobacillus gasseri

RANK: Species

TAXONOMY: Terrabacteria group -> Firmicutes -> Bacilli -> Lactobacillales -> Lactobacillaceae -> Lactobacillus -> Lactobacillus gasseri

OVERVIEW:

Relatively new, this probiotic strain is among the species of Lactobacilli predominantly linked to microflora in the vagina. Women with vaginal discomfort tend to have lower levels of L. gasseri than women with normal vaginal health. L. gasseri also supports digestive health. Research shows that supplementation with a combination of L. gasseri and B. longum helps limit occasional diarrhea in adults.Identified as a constituent of the oral microbiome by Human Oral Microbiome Database. Identified as constituent of vaginal microbiome. [PMID:23282177]

This species has been identified as a resident in the human gastrointestinal tract based on the phylogenetic framework of its small subunit ribosomal RNA gene sequences.[PMC 4262072]

1

COGEM

COGEM released a comprehensive database of pathogenicity assessment of around 2575 bacterial species in 2011. The database ranks the pathogenicity of species on a scale of 1 to 4. Lactobacillus gasseri ranks 1 on this scale: The species or strain does not belong to a recognized group of disease-invoking agents in humans or animals and/or has an extended history of safe usage under conditions without any physical restrictions

TAGS

Keystone	Core species	Type species	Pathogen	Dysbiosis associated	Flora/ commensal	Gut associated	Probiotic
Leanness	Obesity	Skin microbiome	Fecal distribution	Oral microbiome	Vaginal microbiome	Butyrate producer	Catalase producer
Histamine producer	Food fermenter	Amylolytic	Propionate producer	Nitrifying	Biofilm producer

INTERACTIONS INHIBITS Clostridioides difficile Enterococcus	KEGG PATHWAYS CLUSTERS WITH Group 2 Leuconostoc mesenteroides Lactobacillus salivarius Lactobacillus acidophilus Bifidobacterium adolescentis Lactobacillus plantarum Streptococcus thermophilus Oenococcus oeni Listeria monocytogenes Lactobacillus gasseri Chloroflexus aurantiacus Bacillus pumilus Pediococcus pentosaceus Bacillus licheniformis Listeria innocua Lactobacillus sakei Clostridium acetobutylicum Bifidobacterium longum Lactobacillus johnsonii Lactobacillus brevis Lactococcus lactis Streptococcus gordonii Lactobacillus delbrueckii Group 121 Lactobacillus gasseri Lactobacillus brevis Group 107 Lactobacillus johnsonii Lactobacillus gasseri Lactobacillus delbrueckii Group 42 Geobacter uraniumreducens Desulfotomaculum reducens Lactobacillus gasseri Desulfovibrio vulgaris Lawsonia intracellularis Desulfovibrio desulfuricans Thiomicrospira denitrificans Carboxydothermus hydrogenoformans Thermotoga lettingae Group 4 Streptococcus mutans Leuconostoc mesenteroides Lactobacillus salivarius Lactobacillus acidophilus Bifidobacterium adolescentis Streptococcus thermophilus Lactobacillus gasseri Pediococcus pentosaceus Clostridium perfringens Listeria innocua Lactobacillus sakei Bifidobacterium longum Lactobacillus johnsonii Streptococcus sanguinis Lactobacillus casei Lactobacillus brevis Streptococcus gordonii Lactobacillus delbrueckii Group 56 Bifidobacterium adolescentis Lactobacillus johnsonii Bifidobacterium longum Clostridium beijerinckii Streptococcus thermophilus Lactobacillus gasseri Leifsonia xyli Group 178 Streptococcus thermophilus Lactobacillus gasseri Group 148 Lactobacillus salivarius Lactobacillus gasseri	METABOLOMICS NUTRIENTS/ SUBSTRATES Ellagic acid [parent] D-Glucose [parent] CO2 [parent] α-Glucan [parent] ENDPRODUCTS Urolithins [parent] Lactate [parent] Acetylcholine [parent] γ-Amino butyric acid (GABA) [parent] Vitamin B12 [parent] Trimethylamine [parent] Lactic acid [parent] INHIBITED BY Stevia [parent] Laminaria hyperborea (curvie) [parent] Chemotherapy [parent] Magnesium-deficient diet [parent] Glyphosphate [parent] High fat diet [parent] Sucralose (Splenda) [parent] ENHANCED BY Sesame cake/meal [parent] Almonds/ almond skins [parent] Navy bean (Cooked) [parent] Magnesium [parent] a-Glucosidase inhibitors Daesiho-tang (DSHT) [parent] Resveratrol [parent] Proton-pump inhibitors (PPI) [parent] Laminaria digitata (oarweed) [parent] Melatonin [parent] BIOTRANSFORMS Linoleic acid (LA) [parent] Linolenic acid (CLnA) [parent] BIOTRANFORM 10‐Hydroxy‐cis‐12‐octadecenoate (HYA) [parent] Trans-11 conjugate linoleic acid (CLA) [parent] Cis-9 conjugate linoleic acid (CLA) [parent] Cis-15 conjugate linolenic acids (CLnA) [parent] Cis-9 conjugate linolenic acids (CLnA) [parent] 10-Hydroxyoctadecanoate (HYB) [parent] Trans-11 conjugate linolenic acids (CLnA) [parent]
ANTIBIOTIC RESISTANCE See Parent Genus (Lactobacillus)	BIOFILM FORMERS See Parent Genus (Lactobacillus)	COGEM PATHOGENICITY See Parent Genus (Lactobacillus)

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