L. salivarius is somewhat unique among probiotic strains in that it is capable of growing in less than ideal conditions, including environments high in salt, and with or without oxygen. It is found in the oral cavities (mouth, throat, and sinuses), intestines, and vagina, but grows best in the small intestine. Research has shown that people taking L. salivarius had increased markers of immune activity. An additional study found that supplementing with L. salivarius helps to prevent the colonization of undesirable bacteria. Identified as a constituent of the oral microbiome by Human Oral Microbiome Database. Identified as constituent of vaginal microbiome. [PMID:23282177]
This species has been identified as a resident in the human gastrointestinal tract based on the phylogenetic framework of its small subunit ribosomal RNA gene sequences.[PMC 4262072]
COGEM
COGEM released a comprehensive database of pathogenicity assessment of around 2575 bacterial species in 2011. The database ranks the pathogenicity of species on a scale of 1 to 4. Lactobacillus salivarius ranks on this scale:
