Enterobacter cloacae

RANK: Species

TAXONOMY: Bacteria -> Proteobacteria -> Gammaproteobacteria -> Enterobacteriales -> Enterobacteriaceae -> Enterobacter -> Enterobacter cloacae


Enterobacter cloacae is a clinically significant Gram-negative, facultatively-anaerobic, rod-shaped bacterium. In microbiology labs, E. cloacae is frequently grown at 30 °C on nutrient agar or broth or at 35 °C in tryptic soy broth. It is a rod-shaped, Gram-negative bacterium, is facultatively anaerobic, and bears peritrichous flagella. It is oxidase-negative and catalase-positive. Enterobacter cloacae is ornithine decarboxylase positive. Enterobacter cloacae is a member of the normal gut flora of many humans and is not usually a primary pathogen. It is sometimes associated with urinary tract and respiratory tract infections. Treatment with cefepime and gentamicin has been reported.

A 2012 study in which Enterobacter cloacae transplanted into previously germ-free mice resulted in increased obesity when compared with germ-free mice fed an identical diet, suggesting a link between obesity and the presence of Enterobacter gut flora.

This species has been identified as a resident in the human gastrointestinal tract based on the phylogenetic framework of its small subunit ribosomal RNA gene sequences.[PMC 4262072]

Gut associated
Catalase producer
Type species
Enterobacter cloacae enhances growth of
  • Pseudomonas
    Group 192 [Obesity]
  • Enterobacter cloacae