Roseburia intestinalis

RANK: Species

TAXONOMY: Terrabacteria group -> Firmicutes -> Clostridia -> Clostridiales -> Lachnospiraceae -> Roseburia -> Roseburia intestinalis

OVERVIEW:

Roseburia intestinalis is a saccharolytic, butyrate-producing bacterium first isolated from human feces. It is anaerobic, gram-positive, slightly curved rod-shaped and motile by means of multiple subterminal flagella. Roseburia favors and loves starches that escape small intestinal degradation and RS3, cooked-cooled starches. R. intestinalis works synergistically often with Bifidobacteria. Very low carbohydrate diets can cause Roseburia counts to drop, which can cause butyrate to drop as well. Chitin and beta-glucan encourage Roseburia. (as does low dose RS2, green banana flour or RPS). High dose RS2 however will decrease Roseburia (Tachon /2013). Lower concentrations in Type II diabetics.

This species has been identified as a resident in the human gastrointestinal tract based on the phylogenetic framework of its small subunit ribosomal RNA gene sequences.[PMC 4262072]


Gut associated
Core species
Amylolytic
Butyrate producer
INTERACTIONS
METABOLOMICS   
Substrates/ Growth Factors
  • Resistant starch (type II) [parent]
  • N-Acetyl-D-glucosamine [parent]
  • β-Glucan
  • Resistant starch (type III)
  • Acetate [parent]
  • Resistant starch (type II)
  • β-Glucan [parent]
  • Chitin
  • N-Acetyl-D-glucosamine
  • Resistant starch (type III) [parent]
  • Arabinoxylans [parent]
  • Raffinose [parent]
  • Stachyose (soy oligosaccharide) [parent]
  • Chitin [parent]

    • Metabolic Endproducts
  • Lactate [parent]
  • Butyrate [parent]
  • Butyrate

    • Growth Inhibited by
  • High animal protein diet [parent]
  • Low carbohydrate diet [parent]
  • Ketogenic diet [parent]
  • High meat diet [parent]
  • Epinephrine [parent]
  • Fructo-oligosaccharides [parent]

    • Growth Enhanced By
  • Resistant starch (type II) [parent]
  • Almonds/ almond skins [parent]
  • Polymannuronic acid [parent]
  • Vitamin D [parent]
  • N-Acetyl-D-glucosamine [parent]
  • Dopamine [parent]
  • β-Glucan [parent]
  • Walnuts [parent]
  • Arabinoxylans [parent]
  • Dietary fiber [parent]