Lachnospiraceae

RANK: Family

TAXONOMY: cellular organisms -> Bacteria -> Terrabacteria group -> Firmicutes -> Clostridia -> Clostridiales -> Lachnospiraceae

OVERVIEW:

The Lachnospiraceae are oneĀ of the most abundant families from the order Clostridiales found in the mammalian gut environment, and have been associated with the maintenance of gut health. Many members of this family are butyrate producers. A study done in Norway in 2014, found significant correlations between bacteria in stool samples and depression, with elevated levels of the order Bacteroidales and a reduced abundance of the family Lachnospiraceae.

Both secretor status and blood group antigen expression especially affect the Lachnospiraceae family of bacteria within the gut microbiome, with lower abundances noted in nonsecretors and higher abundances in secretors of various blood groups. [PMCID: PMC5625272]

Lachnospiraceae were found to be enhanced in formula-fed infants compared with solely breastfed infants. [PMID: 29868719]


Gut associated
Flora/ commensal
Butyrate producer
Microbial Abundance Data: Lachnospiraceae
Percent of total population with standard deviation [PMID: 22698087]. Percentages > 1% highlighted.
Buccal
Mucosa
Keratinized
Gingiva
Hard
Palate
Throat
Tonsils
Saliva
Stool
0.868 %
(0.997)
0.193 %
(0.368)
2.453 %
(2.065)
5.297 %
(3.762)
4.649 %
(3.423)
4.495 %
(3.300)
6.934 %
(5.696)
DESCENDANTS
INTERACTIONS
Lachnospiraceae enhances growth of
  • Bacteroidales
  • Bacteroides
  • Odoribacter
  • Peptococcaceae

  • Lachnospiraceae inhibits growth of
  • Adlercreutzia
  • Bifidobacterium
  • Blautia
  • Campylobacteraceae
  • Clostridiales Family XIII. Incertae Sedis
  • Clostridiales incertae sedis
  • Clostridium
  • Collinsella
  • Coprococcus
  • Coriobacteriales
  • Dialister
  • Dorea
  • Erysipelotrichaceae
  • Lachnospiraceae
  • Porphyromonas
  • Prevotella
  • Ruminococcaceae
  • Ruminococcus

  • Lachnospiraceae growth inhibited by
  • Acetivibrio
  • Acidaminococcus
  • Adlercreutzia
  • Akkermansia
  • Alcaligenaceae
  • Alistipes
  • Bacteroidales
  • Bacteroides
  • Bifidobacterium
  • Bilophila
  • Blautia
  • Campylobacteraceae
  • Catabacteriaceae
  • Clostridiales
  • Clostridiales Family XIII. Incertae Sedis
  • Clostridiales incertae sedis
  • Clostridium
  • Collinsella
  • Coprococcus
  • Coriobacteriales
  • Desulfovibrio
  • Dialister
  • Dorea
  • Enterobacteriaceae
  • Erysipelotrichaceae
  • Escherichia
  • Eubacterium
  • Faecalibacterium
  • Holdemania
  • Lachnobacterium
  • Lachnospira
  • Lachnospiraceae
  • Odoribacter
  • Oscillospira
  • Oxalobacter
  • Parabacteroides
  • Peptococcaceae
  • Peptoniphilus
  • Phascolarctobacterium
  • Porphyromonadaceae
  • Porphyromonas
  • Prevotella
  • Rikenellaceae
  • Roseburia
  • Rubrivivax
  • Ruminiclostridium
  • Ruminococcaceae
  • Ruminococcus
  • Streptococcus
  • Turicibacter
  • Veillonella
  • METABOLOMICS